INT102111

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Context Info
Confidence 0.45
First Reported 2001
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.14
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bax) endoplasmic reticulum (Bax) intracellular (Bax)
cytoplasm (Bax) cytosol (Bax) cell proliferation (Bax)
Anatomy Link Frequency
muscles 2
Bax (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 2 99.74 Very High Very High Very High
cytokine 3 84.56 Quite High
Inflammation 10 84.16 Quite High
anesthesia 1 62.40 Quite High
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 2 99.74 Very High Very High Very High
Insulin Resistance 9 99.12 Very High Very High Very High
Apoptosis 8 91.76 High High
INFLAMMATION 13 84.16 Quite High
Necrosis 1 82.64 Quite High
Cancer 5 82.28 Quite High
Frailty 19 51.28 Quite High
Hypertrophy 2 50.80 Quite High
Coronary Heart Disease 1 50.68 Quite High
Chronic Renal Failure 28 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ischemia/reperfusion increases the overall expression of both bcl-2 and bax proteins, but bcl-2 is lost from the reperfused area as indicated by TUNEL staining.
Positive_regulation (increases) of Protein_catabolism (proteins) of bax associated with ischemia
1) Confidence 0.45 Published 2001 Journal Jpn Heart J Section Abstract Doc Link 11933925 Disease Relevance 0.61 Pain Relevance 0.15
In studies of muscles from insulin-deficient rats or db/db mice (a model of insulin resistance), we found that accelerated muscle protein degradation increases the level of the proapoptotic factor, Bax [35, 41].
Positive_regulation (increases) of Protein_catabolism (degradation) of Bax in muscles associated with insulin resistance
2) Confidence 0.09 Published 2007 Journal Pediatr Nephrol Section Body Doc Link PMC2259254 Disease Relevance 0.53 Pain Relevance 0.12

General Comments

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