INT102176

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.60
First Reported 2002
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 3.22
Pain Relevance 2.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (FAS) protein complex assembly (FAS) cytoplasm (FAS)
signal transducer activity (FAS) cytosol (FAS) signal transduction (FAS)
Anatomy Link Frequency
T cells 1
FAS (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 9 99.62 Very High Very High Very High
qutenza 14 95.44 Very High Very High Very High
cytokine 4 89.48 High High
agonist 2 87.84 High High
Chronic pancreatitis 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 13 100.00 Very High Very High Very High
Ataxia 2 98.68 Very High Very High Very High
Death 9 98.28 Very High Very High Very High
Adenocarcinoma 3 97.08 Very High Very High Very High
Pancreatitis 4 95.32 Very High Very High Very High
Cancer 12 93.88 High High
Asthma 1 59.68 Quite High
Autoimmune Disease 1 59.24 Quite High
Pancreatic Ductal Carcinoma 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study investigated the mRNA and protein expression of CD97, CD95 and Fas-L in snap-frozen material obtained from human pancreatic ductal adenocarcinomas (PDC; n = 50), tissues from pancreatitis (PT; n = 40) and normal pancreatic tissues (PN; n = 36).
Transcription (expression) of CD95 associated with adenocarcinoma and pancreatitis
1) Confidence 0.60 Published 2002 Journal Pathol. Int. Section Abstract Doc Link 11940212 Disease Relevance 0.61 Pain Relevance 0.07
These events were associated with rapid co-ordinated transcription of pro-apoptotic genes including Fas/CD95, Bcl-2 and caspase families and ataxia telangiectasia mutated (ATM)/CHK2/p53 DNA damage response pathway.
Transcription (transcription) of CD95 associated with ataxia and apoptosis
2) Confidence 0.52 Published 2009 Journal Carcinogenesis Section Abstract Doc Link 19502594 Disease Relevance 0.97 Pain Relevance 0.56
These events were associated with rapid co-ordinated transcription of pro-apoptotic genes including Fas/CD95, Bcl-2 and caspase families and ataxia telangiectasia mutated (ATM)/CHK2/p53 DNA damage response pathway.
Transcription (transcription) of Fas associated with ataxia and apoptosis
3) Confidence 0.52 Published 2009 Journal Carcinogenesis Section Abstract Doc Link 19502594 Disease Relevance 0.97 Pain Relevance 0.55
Furthermore, morphine enhanced the mRNA expression of Fas, FasL and TRAIL and promoted Fas-mediated AICD of CD4(+) T cells.
Transcription (expression) of Fas in T cells associated with death and morphine
4) Confidence 0.34 Published 2005 Journal J. Immunol. Section Abstract Doc Link 16210602 Disease Relevance 0.67 Pain Relevance 0.87

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox