INT102228

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Context Info
Confidence 0.69
First Reported 2002
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 1.58
Pain Relevance 1.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Adm) aging (Adm) extracellular region (Adm)
response to stress (Adm) cytoplasm (Adm)
Anatomy Link Frequency
fascicles 1
artery 1
Adm (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 3 100.00 Very High Very High Very High
Cholecystokinin 1 100.00 Very High Very High Very High
Opioid 1 100.00 Very High Very High Very High
Neuropeptide 10 99.64 Very High Very High Very High
anesthesia 4 96.44 Very High Very High Very High
addiction 5 93.56 High High
Central nervous system 1 72.48 Quite High
Pain 11 71.24 Quite High
Calcitonin gene-related peptide 7 68.80 Quite High
antagonist 1 54.60 Quite High
Disease Link Frequency Relevance Heat
Pancreatitis 80 100.00 Very High Very High Very High
Stress 18 99.62 Very High Very High Very High
Disease 5 96.16 Very High Very High Very High
Sprains And Strains 8 89.44 High High
Injury 6 83.20 Quite High
Cadaver 4 82.56 Quite High
Ulcers 1 81.00 Quite High
Pain 9 71.24 Quite High
Apoptosis 18 66.80 Quite High
Increased Venous Pressure Under Development 1 48.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Adrenomedullin release in the rat mesenteric resistance artery.
Localization (release) of Adrenomedullin in artery associated with qutenza
1) Confidence 0.69 Published 2005 Journal Peptides Section Title Doc Link 15935516 Disease Relevance 0 Pain Relevance 0.34
Harvie et al., found an accessory ADM in 41% of 116 volunteers' asymptomatic ultrasound examinations, greater prevalence being found in male samples and bilateral presentation in 50% of cases for both genders.
Localization (found) of ADM
2) Confidence 0.58 Published 2007 Journal J Brachial Plex Peripher Nerve Inj Section Body Doc Link PMC2245941 Disease Relevance 0 Pain Relevance 0
Murata [7] found an accessory ADM in 35 hands, having one (17%), two (80%) and three fascicles (3%).
Localization (found) of ADM in fascicles
3) Confidence 0.58 Published 2007 Journal J Brachial Plex Peripher Nerve Inj Section Body Doc Link PMC2245941 Disease Relevance 0.08 Pain Relevance 0
Our study demonstrated that the biodegradation time can be controlled by CO(3)Ap contents in the membrane and CO(3)Ap could be released from the membrane with the biodegradation period.
Localization (released) of Ap
4) Confidence 0.21 Published 2002 Journal J. Biomed. Mater. Res. Section Abstract Doc Link 11948524 Disease Relevance 0 Pain Relevance 0.12
To estimate their controlled release of CO(3)Ap in vitro, the membranes (CO(3)Ap 0-10 wt %, 5 x 5 x 0.1 mm) were immersed into collagenase solution and compulsorily dissolved for 48 h.
Localization (release) of Ap
5) Confidence 0.21 Published 2002 Journal J. Biomed. Mater. Res. Section Abstract Doc Link 11948524 Disease Relevance 0 Pain Relevance 0.13
The aim of this study was to investigate the biodegradation of carbonate apatite (CO(3)Ap)/collagen composite membrane as a new guided tissue regeneration membrane in vivo and to estimate its controlled release of CO(3)Ap in vitro.
Localization (release) of Ap
6) Confidence 0.21 Published 2002 Journal J. Biomed. Mater. Res. Section Abstract Doc Link 11948524 Disease Relevance 0 Pain Relevance 0.07
Centrally and /or peripherally injected neuropeptides, such as amylin, adrenomedullin, bombesin, cholecystokinin, neurotensin, opioid peptides, thyreotropin releasing hormone and vasoactive intestinal peptide, influence both the acid secretion and the gastric mucosal lesions induced by different ulcerogens.
Localization (secretion) of adrenomedullin associated with neuropeptide, opioid and cholecystokinin
7) Confidence 0.07 Published 2004 Journal Curr Top Med Chem Section Abstract Doc Link 14754377 Disease Relevance 0.16 Pain Relevance 0.61
In addition, the role of oxidative stress has been evaluated in experimental models of acute pancreatitis [43] and it should be emphasized that oxidative stress and excessive ROS generation are early features in AP and consequently a difficult target for clinical prophylaxis to prevent a severe course of the disease.
Localization (generation) of AP associated with stress, pancreatitis and disease
8) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2639703 Disease Relevance 1.26 Pain Relevance 0
I-CVI and ADM results for other individual elements (e.g., title, administration instructions, scoring instructions, record form) of the IDUQOL measure and manual are presented in Table 4.
Localization (presented) of ADM
9) Confidence 0.03 Published 2007 Journal Health Qual Life Outcomes Section Body Doc Link PMC1994946 Disease Relevance 0.07 Pain Relevance 0.07

General Comments

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