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Context Info
Confidence 0.41
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (EPO, HIF1A) cell differentiation (HIF1A) aging (EPO)
cytoplasm (HIF1A) signal transducer activity (HIF1A) extracellular space (EPO)
EPO (Homo sapiens)
HIF1A (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 1 72.16 Quite High
palliative 1 36.16 Quite Low
Disease Link Frequency Relevance Heat
Hypoxia 5 100.00 Very High Very High Very High
Cancer 5 82.00 Quite High
Necrosis 1 81.52 Quite High
INFLAMMATION 1 72.16 Quite High
Anaemia 3 62.40 Quite High
Autoimmune Disease 1 45.68 Quite Low
Solid Tumor 1 39.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The EPO gene enhancer (like the flanking DNA-elements of several other pO2-controlled genes) contains a consensus sequence (CGTG) that binds the trans-acting dimeric hypoxia-inducible factor 1 (HIF-1alpha/beta).
EPO Binding (binds) of HIF-1 associated with hypoxia
1) Confidence 0.41 Published 2001 Journal Adv. Exp. Med. Biol. Section Abstract Doc Link 11950137 Disease Relevance 0.65 Pain Relevance 0.04

General Comments

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