INT102354

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.75
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.17
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (TWIST1) DNA binding (TWIST1) transcription factor binding (TWIST1)
TWIST1 (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal-cord stimulation 8 100.00 Very High Very High Very High
Abeta 3 83.40 Quite High
Dorsal column 1 32.04 Quite Low
Pain 1 25.00 Low Low
Adelta 1 25.00 Low Low
c fibre 1 25.00 Low Low
cytokine 5 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 49 60.16 Quite High
Injury 11 55.96 Quite High
Prostate Cancer 53 51.52 Quite High
Hypertrophy 9 40.24 Quite Low
Pain 1 25.00 Low Low
Metastasis 18 5.00 Very Low Very Low Very Low
Disease 17 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The largest DLC(0-300) fibres are not likely to be recruited by SCS, since they are not larger than their DC(0-300) counterparts, they lack collaterals (which would reduce the threshold stimulus substantially) and they are more remote from the stimulation electrode.
Localization (recruited) of SCS associated with spinal-cord stimulation
1) Confidence 0.75 Published 2002 Journal Brain Section Abstract Doc Link 11960902 Disease Relevance 0 Pain Relevance 0.15
Validated primers and probes from TaqMan Gene Expression Assays (Applied Biosystems) were used for quantification of VAV3 (Hs00916821_m1), TWIST1 (Hs00361186_m1), DKK3 (Hs00951307_m1) and GAPDH (Hs99999905_m1), according to the PCR settings provided by Applied Biosystems.
Localization (quantification) of TWIST1
2) Confidence 0.61 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2957443 Disease Relevance 0.11 Pain Relevance 0
Immunofluorescent triple staining of Pax7, IL-6, and DAPI, revealed a substantial increase in the localization of IL-6 protein within SCs (see Fig.
Localization (localization) of SCs
3) Confidence 0.16 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2696599 Disease Relevance 0.06 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox