INT102414

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Context Info
Confidence 0.29
First Reported 1999
Last Reported 2008
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.95
Pain Relevance 1.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neurons 1
SM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
electroacupuncture 5 100.00 Very High Very High Very High
Opioid 3 99.06 Very High Very High Very High
narcan 2 98.92 Very High Very High Very High
nociceptor 1 98.92 Very High Very High Very High
fibrosis 9 97.48 Very High Very High Very High
Acupuncture 1 89.40 High High
analgesia 3 88.92 High High
opiate 2 87.60 High High
antagonist 2 77.20 Quite High
addiction 2 75.76 Quite High
Disease Link Frequency Relevance Heat
Nociception 4 98.96 Very High Very High Very High
Fibrosis 8 97.48 Very High Very High Very High
Schistosomiasis 21 84.36 Quite High
Pressure And Volume Under Development 2 83.60 Quite High
Cirrhosis 1 82.64 Quite High
Infection 82 57.68 Quite High
Peripheral Arterial Disease 1 50.00 Quite Low
Disease 7 38.52 Quite Low
Helminth Infection 22 5.00 Very Low Very Low Very Low
Asthma 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To localize SM2, the authors genotyped all the informative families with multiple cases of severe fibrosis (8 families including 112 individuals) and linkage analysis was done in four candidate regions: (1) the 5q31-q33 region were SM1 and several candidate genes are localized; (2) the HLA-TNF region (6p21) containing the HLA locus and the genes coding for TNF-?
Localization (localized) of SM1 associated with fibrosis
1) Confidence 0.29 Published 2008 Journal Current Genomics Section Body Doc Link PMC2685643 Disease Relevance 0.64 Pain Relevance 0.31
[Opioid mu receptors in caudate nucleus contribute to electroacupuncture and Sm I generating inhibition on nociceptive responses of Pf neurons].
Localization (electroacupuncture) of Sm I in neurons associated with nociception, narcan, electroacupuncture and opioid
2) Confidence 0.12 Published 1999 Journal Sheng Li Xue Bao Section Title Doc Link 11972175 Disease Relevance 0.31 Pain Relevance 1.12

General Comments

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