INT102522

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Context Info
Confidence 0.71
First Reported 2002
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 3.72
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cd63) protein complex (Cd63) lysosome (Cd63)
cytoplasm (Cd63)
Anatomy Link Frequency
basophil 3
platelets 1
respiratory 1
Cd63 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 3 100.00 Very High Very High Very High
anesthesia 3 95.24 Very High Very High Very High
Angina 3 95.20 Very High Very High Very High
cINOD 3 88.04 High High
antagonist 1 29.36 Quite Low
Percutaneous transluminal coronary angioplasty 4 25.04 Quite Low
COX2 1 25.00 Low Low
Inflammation 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Heart Rate Under Development 3 100.00 Very High Very High Very High
Anaphylaxis 10 99.28 Very High Very High Very High
Adenoma 15 98.32 Very High Very High Very High
Carcinoma 1 97.88 Very High Very High Very High
Myocardial Infarction 9 97.32 Very High Very High Very High
Cv General 3 Under Development 3 95.20 Very High Very High Very High
Reprotox - General 3 1 92.32 High High
Polyps 5 91.44 High High
INFLAMMATION 3 87.80 High High
Colon Cancer 1 77.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Anaphylaxis to vecuronium: the use of basophil CD63 expression as a possible screening tool to identify a safe alternative.
Gene_expression (expression) of CD63 in basophil associated with anaphylaxis
1) Confidence 0.71 Published 2007 Journal J Clin Anesth Section Title Doc Link 18063215 Disease Relevance 0.29 Pain Relevance 0.10
We performed flow cytometric analysis of the expression on the cell surface of the basophil activation markers CD63 and CD203c and measured histamine release in 21 patients who were referred with possible peri-operative anaphylaxis.
Gene_expression (expression) of CD63 in basophil associated with anaphylaxis
2) Confidence 0.50 Published 2005 Journal Anaesthesia Section Abstract Doc Link 15710010 Disease Relevance 0.34 Pain Relevance 0
These results demonstrate the difficulty in investigating the cause of an unexpected clinical event following drug administration, but the higher sensitivity of neo-expression on the cell surface of CD63 suggests that flow cytometric analysis of its neo-expression on basophils in vitro may be a diagnostic aid.
Gene_expression (expression) of CD63 in basophils
3) Confidence 0.50 Published 2005 Journal Anaesthesia Section Abstract Doc Link 15710010 Disease Relevance 0.29 Pain Relevance 0
In eosinophils, indomethacin induced chemotaxis, CD11b up-regulation, respiratory burst, and L-selectin shedding but did not cause up-regulation of CD63 expression.
Gene_expression (expression) of CD63 in respiratory
4) Confidence 0.15 Published 2002 Journal J. Biol. Chem. Section Abstract Doc Link 11980903 Disease Relevance 0.15 Pain Relevance 0.13
The levels of platelet-derived microparticles (PDMPs), platelet activation markers (P-selectin, CD63, and PAC-1 on activated platelets), and C-C chemokines (monocyte chemotactic peptide [MCP]-1 and regulated on activation normally T-cell expressed and secreted [RANTES] were measured and compared in patients with acute myocardial infarction (AMI) or stable pectoris angina.
Gene_expression (expressed) of CD63 in platelets associated with chemokine, heart rate under development, angina and myocardial infarction
5) Confidence 0.13 Published 2002 Journal Clin. Appl. Thromb. Hemost. Section Abstract Doc Link 12361207 Disease Relevance 0.81 Pain Relevance 0.25
Regarding the immunohistochemical expression of p53, MIB-1, and CD63, histological classification was made for each case.
Gene_expression (expression) of CD63
6) Confidence 0.06 Published 2005 Journal Pathol. Res. Pract. Section Abstract Doc Link 16136748 Disease Relevance 1.83 Pain Relevance 0.16

General Comments

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