INT1026

Context Info Confidence 0.48 First Reported 1975 Last Reported 2010 Negated 19 Speculated 11 Reported most in Body Documents 207 Total Number 218 Disease Relevance 150.96 Pain Relevance 119.16

lipid binding (Lbp) transport (Lbp) extracellular space (Lbp) extracellular region (Lbp)

Anatomy Link Frequency body 8 spine 5 spinal 4 trunk muscle 3 muscle 2 Lbp (Rattus norvegicus)

Pain Link Frequency Relevance Heat backache 8786 100.00 alcohol 724 100.00 headache 308 100.00 Chronic low back pain 135 100.00 Sciatica 42 100.00 shoulder pain 35 100.00 Fibrositis 184 99.92 Pain 1216 99.52 behavioral therapy 22 99.28 abdominal pain 6 98.00

Disease Link Frequency Relevance Heat Low Back Pain 8994 100.00 Nicotine Addiction 1579 100.00 Obesity 746 100.00 Overweight 537 100.00 Headache 320 100.00 Disease 257 100.00 Nerve Root Compression 44 100.00 Shoulder Pain 36 100.00 Syndrome 24 100.00 Congenital Anomalies 15 99.98

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Walking/bicycling more than 8 km weekly to regular activities was inversely associated with LBP in multivariate analysis (OR 0.3; 95% confidence interval 0.1-1.0).

LBP Binding (associated) of associated with backache

1) Confidence 0.48 Published 2003 Journal Eur Spine J Section Abstract Doc Link 12928857 Disease Relevance 0.60 Pain Relevance 0.68

Therefore, we find it important to shift focus from risk factors associated with LBP in adult life to early predictors for LBP.

LBP Binding (associated) of associated with backache

2) Confidence 0.48 Published 2006 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1431536 Disease Relevance 1.32 Pain Relevance 1.04

We used multiple logistic regression models to examine the association between spondylolysis, spondylolisthesis, and LBP, while adjusting for gender, age, and BMI.

LBP Spec (examine) Binding (association) of

3) Confidence 0.48 Published 2009 Journal Spine Section Body Doc Link 19139672 Disease Relevance 0 Pain Relevance 0

We studied growth for its association with the incidence of LBP in a population study of 430 children who were examined five times: at the age 11,12,13,14 and 22 years.

LBP Binding (association) of associated with backache

4) Confidence 0.48 Published 2005 Journal Eur Spine J Section Abstract Doc Link 15789230 Disease Relevance 0.87 Pain Relevance 0.70

The association between LBP and neuromuscular imbalance still remains unclear.

LBP Binding (association) of associated with backache

5) Confidence 0.48 Published 2006 Journal Spine J Section Abstract Doc Link 17088198 Disease Relevance 0.17 Pain Relevance 0.37

One hundred eighty-eight individuals were consecutively enrolled in this study to assess radiographic features potentially associated with LBP.

LBP Binding (associated) of

6) Confidence 0.48 Published 2009 Journal Spine Section Body Doc Link 19139672 Disease Relevance 0 Pain Relevance 0

LBP is often associated with other pain manifestations such as headache, abdominal pain and pain in different locations of the extremities.

LBP Binding (associated) of associated with pain, abdominal pain, headache and backache

7) Confidence 0.48 Published 2007 Journal Best Pract Res Clin Rheumatol Section Abstract Doc Link 17350545 Disease Relevance 1.74 Pain Relevance 1.56

The estimates of the association between physical demands and LBP have therefore been controlled for differences in psychosocial work factors.

LBP Binding (association) of associated with backache

8) Confidence 0.48 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2390553 Disease Relevance 0.42 Pain Relevance 0.37

On the contrary, no significant association between LBP and maximum isometric trunk extension strength or neuromuscular imbalance and maximum isometric trunk extension strength was found before or after the exercise program.

LBP Neg (no) Binding (association) of in trunk

9) Confidence 0.48 Published 2006 Journal Spine J Section Body Doc Link 17088198 Disease Relevance 0 Pain Relevance 0

Patients with longer sick leave account for most costs associated with LBP.

LBP Binding (associated) of associated with backache

10) Confidence 0.48 Published 2009 Journal Spine J Section Abstract Doc Link 19837008 Disease Relevance 0.46 Pain Relevance 0.55

Significant associations between LBP and digestive and respiratory disorders were revealed, indicating that LBP and these disease entities may have etiological factors in common.

LBP Binding (associations) of in respiratory associated with disease and backache

11) Confidence 0.48 Published 2005 Journal Ann Agric Environ Med Section Abstract Doc Link 16457483 Disease Relevance 1.10 Pain Relevance 0.69

SUMMARY OF BACKGROUND DATA: Smoking has been found to associate with LBP among adults.

LBP Binding (associate) of

12) Confidence 0.48 Published 2008 Journal Spine Section Body Doc Link 18317198 Disease Relevance 0 Pain Relevance 0

Univariate analyses followed by multiple logistic regression analyses were used to explore the risk factors associated with LBP cases.

LBP Binding (associated) of

13) Confidence 0.47 Published 2006 Journal J Occup Rehabil Section Body Doc Link 16705492 Disease Relevance 0.15 Pain Relevance 0

A stepwise logistic regression analysis was carried out to determine the risk factors associated with LBP and chronic LBP.

LBP Binding (associated) of associated with backache

14) Confidence 0.47 Published 2005 Journal Eur Spine J Section Abstract Doc Link 15940479 Disease Relevance 1.27 Pain Relevance 1.20

In multivariate analyses, LBP was inversely associated with time spent on physical activity, in particular with regular walking or bicycling.

LBP Binding (associated) of associated with backache

15) Confidence 0.47 Published 2004 Journal Scand J Med Sci Sports Section Abstract Doc Link 15546330 Disease Relevance 0.60 Pain Relevance 0.67

After adjustment for age, the average duration of sleep was associated with LBP.

LBP Binding (associated) of associated with backache

16) Confidence 0.46 Published 2007 Journal BMC Public Health Section Body Doc Link PMC1971070 Disease Relevance 1.47 Pain Relevance 1.08

According to our logistic regression analyses, LBP was associated with several risk factors.

LBP Binding (associated) of associated with backache

17) Confidence 0.46 Published 2007 Journal BMC Public Health Section Body Doc Link PMC1971070 Disease Relevance 0.90 Pain Relevance 0.90

It was noteworthy that LBP was associated with gender after adjustment for all factors.

LBP Binding (associated) of associated with backache

18) Confidence 0.46 Published 2007 Journal BMC Public Health Section Body Doc Link PMC1971070 Disease Relevance 0.96 Pain Relevance 0.96

Therefore studies evaluating the risk factors associated with LBP are inconclusive.

LBP Binding (associated) of associated with backache

19) Confidence 0.46 Published 2007 Journal BMC Public Health Section Body Doc Link PMC1971070 Disease Relevance 0.85 Pain Relevance 0.79

Available literature about the association of LBP with regular sports/physical activity is inconclusive.

LBP Binding (association) of associated with backache

20) Confidence 0.46 Published 2007 Journal BMC Public Health Section Body Doc Link PMC1971070 Disease Relevance 1.67 Pain Relevance 1.16

General Comments

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