INT10262

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Context Info
Confidence 0.86
First Reported 1989
Last Reported 1992
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.30
Pain Relevance 1.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Pd (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 7 100.00 Very High Very High Very High
Analgesic 2 99.60 Very High Very High Very High
Pain 1 99.60 Very High Very High Very High
MU agonist 1 98.62 Very High Very High Very High
Physical dependence 4 97.64 Very High Very High Very High
Antinociceptive 2 95.80 Very High Very High Very High
narcan 3 76.24 Quite High
opioid receptor 1 76.08 Quite High
antagonist 1 75.44 Quite High
withdrawal 1 74.96 Quite High
Disease Link Frequency Relevance Heat
Drug Dependence 4 97.64 Very High Very High Very High
Opiate Addiction 1 74.96 Quite High
Tremor 1 51.92 Quite High
Weight Loss 1 49.12 Quite Low
Body Weight Changes 1 39.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Development of physical dependence is observed after treatment with opioid agonists, but not after chronic i.c.v. administration of mixed inhibitors of enkephalin-degrading enzymes.
Protein_catabolism (degrading) of enkephalin-degrading associated with mu agonist, physical dependence and enkephalin
1) Confidence 0.86 Published 1992 Journal Eur. J. Pharmacol. Section Abstract Doc Link 1478261 Disease Relevance 0.30 Pain Relevance 0.53
Novel inhibitors of enkephalin-degrading enzymes.
Protein_catabolism (degrading) of enkephalin-degrading associated with analgesic and enkephalin
2) Confidence 0.04 Published 1989 Journal J. Enzym. Inhib. Section Title Doc Link 2489237 Disease Relevance 0 Pain Relevance 0.62

General Comments

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