INT102636

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Context Info
Confidence 0.05
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.19
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Sigmar1) nuclear envelope (Sigmar1) lipid particle (Sigmar1)
endoplasmic reticulum (Sigmar1) plasma membrane (Sigmar1) nucleus (Sigmar1)
Sigmar1 (Rattus norvegicus)
Mir377 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nMDA receptor 6 75.00 Quite High
fortral 2 36.56 Quite Low
Disease Link Frequency Relevance Heat
Psychosis 4 99.70 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MS-377 ((R)-(+)-1-(4-chlorophenyl)-3-[4-(2-methoxyethyl)piperazin-1-yl]methyl-2-pyrrolidinone L-tartrate) is a antipsychotic agent that binds to sigma-1 receptor.
sigma-1 receptor Binding (binds) of MS-377
1) Confidence 0.05 Published 2002 Journal Life Sci. Section Abstract Doc Link 11991251 Disease Relevance 0.09 Pain Relevance 0.04
These anti-psychotic activities of MS-377 are attributable to association with sigma-1 receptor.
sigma-1 receptor Binding (association) of MS-377 associated with psychosis
2) Confidence 0.05 Published 2002 Journal Life Sci. Section Abstract Doc Link 11991251 Disease Relevance 0.10 Pain Relevance 0.04

General Comments

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