INT10265

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Context Info
Confidence 0.33
First Reported 1984
Last Reported 2005
Negated 4
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 0.35
Pain Relevance 2.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Sst) extracellular region (Sst)
Anatomy Link Frequency
pancreas 2
posterior 2
Sst (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 44 100.00 Very High Very High Very High
Morphine 5 96.88 Very High Very High Very High
tetrodotoxin 10 96.20 Very High Very High Very High
Central nervous system 1 91.60 High High
antagonist 1 89.36 High High
c fibre 2 71.60 Quite High
GABAergic 1 27.04 Quite Low
nociceptor 3 25.00 Low Low
Migraine 1 25.00 Low Low
Cluster headache 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 4 99.32 Very High Very High Very High
Hyperinsulinism 2 83.04 Quite High
Headache 1 5.00 Very Low Very Low Very Low
Cluster Headache 1 5.00 Very Low Very Low Very Low
Primary Headache Disorders 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Non-adrenergic non-cholinergic effects do not participate in regulation of glucagon and somatostatin secretion under the conditions employed.
Neg (not) Regulation (participate) of Regulation (regulation) of somatostatin associated with somatostatin
1) Confidence 0.33 Published 1992 Journal Diabetologia Section Abstract Doc Link 1478364 Disease Relevance 0 Pain Relevance 0.31
As shown previously, atropine had an identical effect on gastrin and somatostatin responses to transmural electrical stimulation of the antral region.
Regulation (effect) of Regulation (effect) of somatostatin associated with somatostatin
2) Confidence 0.31 Published 1984 Journal Gastroenterology Section Abstract Doc Link 6146551 Disease Relevance 0 Pain Relevance 0.32
We studied the effects of somatostatin receptor modulation in the posterior hypothalamic area (PH) of the rat on dural nociceptive input.
Regulation (effects) of Regulation (modulation) of somatostatin in posterior associated with nociception and somatostatin
3) Confidence 0.25 Published 2005 Journal Pain Section Abstract Doc Link 16043293 Disease Relevance 0.27 Pain Relevance 0.61
This shows that morphine induces the release of insulin, glucagon and somatostatin from pancreas in a dose-dependent way, and that release of insulin and glucagon is not primarily affected by regulation of somatostatin levels.
Neg (not) Regulation (affected) of Regulation (regulation) of somatostatin in pancreas associated with somatostatin and morphine
4) Confidence 0.24 Published 1994 Journal Res Exp Med (Berl) Section Abstract Doc Link 7800932 Disease Relevance 0 Pain Relevance 0.65
Atropine partially inhibited the gastrin response (34 +/- 6%) but had no effect on the somatostatin response.
Neg (no) Regulation (effect) of Regulation (response) of somatostatin associated with somatostatin
5) Confidence 0.24 Published 1987 Journal Am. J. Physiol. Section Abstract Doc Link 2892415 Disease Relevance 0 Pain Relevance 0.47
In contrast the combined adrenergic and cholinergic blockade with atropine, phentolamine and propranolol (10(-5) mol/l) did not modify the insulin, glucagon and somatostatin response.
Neg (not) Regulation (modify) of Neg (not) Regulation (response) of somatostatin associated with somatostatin
6) Confidence 0.20 Published 1992 Journal Diabetologia Section Abstract Doc Link 1478364 Disease Relevance 0.08 Pain Relevance 0.56

General Comments

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