INT102698

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Context Info
Confidence 0.42
First Reported 1999
Last Reported 2010
Negated 4
Speculated 2
Reported most in Body
Documents 54
Total Number 58
Disease Relevance 66.73
Pain Relevance 9.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

biosynthetic process (ACCS)
Anatomy Link Frequency
chest 3
heart 3
myocyte 2
hair 2
coronary artery 1
ACCS (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 219 100.00 Very High Very High Very High
cytokine 172 100.00 Very High Very High Very High
Angina 613 99.38 Very High Very High Very High
Pain 95 98.72 Very High Very High Very High
Inflammation 130 98.36 Very High Very High Very High
metalloproteinase 7 95.04 Very High Very High Very High
depression 188 85.44 High High
ischemia 52 77.28 Quite High
Snapping jaw 1 74.44 Quite High
beta blocker 31 71.56 Quite High
Disease Link Frequency Relevance Heat
Acute Coronary Syndrome 1611 100.00 Very High Very High Very High
Myocardial Infarction 571 100.00 Very High Very High Very High
Diabetes Mellitus 448 100.00 Very High Very High Very High
Compartment Syndromes 229 100.00 Very High Very High Very High
Syndrome 114 100.00 Very High Very High Very High
Pulmonary Embolism 76 100.00 Very High Very High Very High
Delirium 65 100.00 Very High Very High Very High
Systemic Lupus Erythematosus 175 99.90 Very High Very High Very High
Increased Venous Pressure Under Development 41 99.84 Very High Very High Very High
Necrosis 64 99.44 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The timely recognition of ACS of the lower leg can be difficult because it can be caused by minimal trauma or masked by a concomitant trauma [1, 2].
ACS Binding (recognition) of in lower leg associated with compartment syndromes and injury
1) Confidence 0.42 Published 2010 Journal The Open Orthopaedics Journal Section Body Doc Link PMC2851121 Disease Relevance 1.03 Pain Relevance 0.17
AA, PB, ACS, CAL, HB have made substantial contributions to conception and design
ACS Binding (made) of
2) Confidence 0.36 Published 2007 Journal BMC Cardiovasc Disord Section Body Doc Link PMC1894986 Disease Relevance 0.65 Pain Relevance 0
No chromosomal rearrangements have been associated with ACS, thus mapping and positional cloning is the best approach to identify this disease gene.
ACS Binding (associated) of associated with syndrome and disease
3) Confidence 0.36 Published 2008 Journal Eur. J. Hum. Genet. Section Abstract Doc Link 18000524 Disease Relevance 1.14 Pain Relevance 0.07
As early as possible, one has to think of the ACS, so that treatment may be begun as early as possible [16].
ACS Binding (think) of associated with compartment syndromes
4) Confidence 0.32 Published 2010 Journal The Open Orthopaedics Journal Section Body Doc Link PMC2851121 Disease Relevance 1.20 Pain Relevance 0
No gold standard exists for diagnosing ACS.
ACS Binding (diagnosing) of associated with compartment syndromes
5) Confidence 0.32 Published 2010 Journal The Open Orthopaedics Journal Section Body Doc Link PMC2851121 Disease Relevance 1.13 Pain Relevance 0.19
Acute compartment syndrome (ACS) of the lower leg that is not recognized and left untreated can lead to loss of the affected extremity.
ACS Neg (not) Binding (recognized) of in extremity associated with compartment syndromes
6) Confidence 0.32 Published 2010 Journal The Open Orthopaedics Journal Section Body Doc Link PMC2851121 Disease Relevance 0.70 Pain Relevance 0.05
Thus, although a single lesion is clinically symptomatic, ACS seems to be associated with global coronary instability.
ACS Binding (associated) of associated with acute coronary syndrome
7) Confidence 0.31 Published 2002 Journal Arch Mal Coeur Vaiss Section Abstract Doc Link 11998329 Disease Relevance 1.21 Pain Relevance 0.06
Unstable angina and acute coronary syndromes (ACS) without ST-segment elevation are frequent in the elderly and is associated to a very poor prognosis.
ACS Binding (associated) of associated with acute coronary syndrome and angina
8) Confidence 0.31 Published 2006 Journal Arch Mal Coeur Vaiss Section Abstract Doc Link 17236467 Disease Relevance 0.76 Pain Relevance 0.10
If advances in coronary disease are to occur, it is important to recognize the precursor lesion of ACS.
ACS Binding (recognize) of associated with acute coronary syndrome and coronary heart disease
9) Confidence 0.30 Published 2006 Journal J. Am. Coll. Cardiol. Section Abstract Doc Link 16631505 Disease Relevance 1.42 Pain Relevance 0.09
The Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the American College of Cardiology/American Heart Association Guidelines (CRUSADE) initiative is a prospective, rapid-cycle quality-improvement initiative that focuses on improving both the diagnostic evaluation of patients with non-ST-segment elevation (NSTE) acute coronary syndromes (ACS; defined as ischemic ST-segment changes and/or positive cardiac markers) and the use of treatments recommended by the American College of Cardiology (ACC)/American Heart Association (AHA) guidelines for management of NSTE ACS.
NSTE ACS Binding (management) of in Heart associated with acute coronary syndrome, angina and cv general 3 under development
10) Confidence 0.27 Published 2006 Journal Am. J. Cardiol. Section Abstract Doc Link 17169628 Disease Relevance 0.33 Pain Relevance 0.16
Only recently has the important role of abdominal compartment syndrome (ACS) been recognized as a contributing factor to the multiple organ failure commonly seen in severe acute pancreatitis (SAP).
ACS Binding (recognized) of associated with multiple organ failure, compartment syndromes and pancreatitis
11) Confidence 0.23 Published 2008 Journal World J Emerg Surg Section Abstract Doc Link PMC2266717 Disease Relevance 1.20 Pain Relevance 0
If not recognized and treated in timely manner, ACS can result in multiorgan system failure and death.
ACS Binding (recognized) of associated with compartment syndromes and death
12) Confidence 0.22 Published 1999 Journal Crit Care Section Body Doc Link PMC29028 Disease Relevance 0.97 Pain Relevance 0
Odds ratios (OR) were calculated for the association between each potential risk factor and ACS.
ACS Binding (association) of associated with acute coronary syndrome
13) Confidence 0.20 Published 2006 Journal BMC Med Inform Decis Mak Section Body Doc Link PMC1559601 Disease Relevance 0.99 Pain Relevance 0.14
Associations with ACS were also indicated for gender, angina pectoris, treatment with cardiac drugs, tachypnea, lung rales, and blood pressure, whereas no clear associations with smoking status, diabetes, congestive heart failure, previous PCI, previous CABG and heart rate were discerned.
ACS Spec (clear) Binding (Associations) of in heart associated with heart rate under development, acute coronary syndrome, angina, nicotine addiction, respiratory sounds and diabetes mellitus
14) Confidence 0.20 Published 2006 Journal BMC Med Inform Decis Mak Section Body Doc Link PMC1559601 Disease Relevance 1.11 Pain Relevance 0.16
When each potential risk factor was considered separately, significant associations with ACS were observed for age, hypertension, previous myocardial infarction, chest discomfort at presentation, and symptom duration (table 1).
ACS Binding (associations) of in chest associated with acute coronary syndrome, hypertension and myocardial infarction
15) Confidence 0.20 Published 2006 Journal BMC Med Inform Decis Mak Section Body Doc Link PMC1559601 Disease Relevance 0.83 Pain Relevance 0.08
Moreover, congestive heart failure and previous CABG were inversely associated with ACS.
ACS Binding (associated) of in heart associated with acute coronary syndrome and heart rate under development
16) Confidence 0.20 Published 2006 Journal BMC Med Inform Decis Mak Section Body Doc Link PMC1559601 Disease Relevance 1.45 Pain Relevance 0.16
Our report finally indicates that ACS can occur outside the typical setting of abdominal surgery or trauma, decompressive laparotomy is not always the gold standard and patients with VADs may be at high risk for postoperative IAH and ACS.


ACS Binding (risk) of associated with compartment syndromes and injury
17) Confidence 0.19 Published 2010 Journal J Cardiothorac Surg Section Body Doc Link PMC2992055 Disease Relevance 0.88 Pain Relevance 0
CONCLUSIONS: Regional LVF assessment at rest improves diagnostic accuracy for ACS in patients with acute chest pain, especially in those with coronary artery disease and thus may be helpful to guide further management in patients at intermediate risk for ACS.


ACS Binding (accuracy) of in coronary artery
18) Confidence 0.16 Published 2010 Journal Circ Cardiovasc Imaging Section Body Doc Link 20484542 Disease Relevance 0 Pain Relevance 0
The area under ROC, measured in percent, can be interpreted as the probability that a randomly chosen patient with ACS has a higher outcome probability than a randomly chosen patient without ACS.
ACS Binding (patient) of associated with acute coronary syndrome
19) Confidence 0.16 Published 2006 Journal BMC Med Inform Decis Mak Section Body Doc Link PMC1559601 Disease Relevance 0.42 Pain Relevance 0
Weak evidence was found to suggest that RACPCs may be associated with reduced admission to hospital of patients with non-cardiac pain, better recognition of ACS, earlier specialist assessment of exertional angina and earlier diagnosis of non-cardiac chest pain.
ACS Binding (recognition) of in chest
20) Confidence 0.15 Published 2004 Journal Health Technol Assess Section Body Doc Link 14754562 Disease Relevance 0 Pain Relevance 0

General Comments

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