INT1027

Context Info Confidence 0.77 First Reported 1975 Last Reported 2010 Negated 6 Speculated 8 Reported most in Body Documents 132 Total Number 140 Disease Relevance 106.70 Pain Relevance 54.16

lipid binding (Lbp) transport (Lbp) extracellular space (Lbp) extracellular region (Lbp)

Anatomy Link Frequency muscle 6 mere 3 leg 3 liver 3 spine 3 Lbp (Rattus norvegicus)

Pain Link Frequency Relevance Heat backache 4185 100.00 Pain 1132 100.00 Chronic low back pain 123 100.00 Fibrositis 157 99.74 metalloproteinase 24 99.64 alcohol 38 99.36 rheumatoid arthritis 126 99.30 imagery 212 99.20 Facet joint 10 99.20 Inflammatory marker 108 98.66

Disease Link Frequency Relevance Heat Low Back Pain 4349 100.00 Pain 1174 100.00 Sepsis 2192 99.92 Cognitive Disorder 52 99.92 Aging 17 99.80 Obesity 147 99.76 Fibromyalgia 157 99.74 Pressure And Volume Under Development 165 99.72 Apoptosis 30 99.64 Injury 82 99.50

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The results suggest that sociocultural factors influence the expression of LBP, but not the risk of chronicity once LBP is reported, and that work satisfaction may not be causally related to LBP, but may intervene along with type of occupation in the possibility of continuing employment once LBP is present.

Gene_expression (expression) of LBP associated with backache

1) Confidence 0.77 Published 1994 Journal Spine Section Abstract Doc Link 8153818 Disease Relevance 1.48 Pain Relevance 1.48

There are two major differences between the outcomes produced by behavioral interventions for LBP and those produced by interventions for RA and OA.

Gene_expression (produced) of LBP associated with rheumatoid arthritis

2) Confidence 0.77 Published 1994 Journal Bull Rheum Dis Section Abstract Doc Link 8087200 Disease Relevance 0.90 Pain Relevance 0.35

Most synthesis of LBP intervention data has been via systematic review.

Gene_expression (synthesis) of LBP associated with backache

3) Confidence 0.77 Published 2005 Journal Chiropr Osteopat Section Body Doc Link PMC1208926 Disease Relevance 0.78 Pain Relevance 0.70

The literature, however, fails to conclusively document the role of the facet in the production of LBP.

Gene_expression (production) of LBP in facet associated with backache

4) Confidence 0.76 Published 1992 Journal Clin. Orthop. Relat. Res. Section Abstract Doc Link 1534721 Disease Relevance 0.73 Pain Relevance 0.76

The COPE LBP trial: Cognitive Patient Education for Low Back Pain - a cluster randomized controlled trial in primary care Background

Gene_expression (trial) of LBP associated with low back pain, pain and cognitive disorder

5) Confidence 0.67 Published 2010 Journal BMC Musculoskelet Disord Section Title Doc Link PMC2839981 Disease Relevance 1.08 Pain Relevance 0.76

Of the 111, 75% continued to have LBP postpartum and at the 90-day post-delivery follow-up, 54% of those with LBP during pregnancy were still experiencing LBP.

Gene_expression (experiencing) of LBP associated with backache

6) Confidence 0.67 Published 2000 Journal J Obstet Gynaecol Section Abstract Doc Link 15512548 Disease Relevance 1.54 Pain Relevance 1.20

LBP is found in both sedentary occupations and in drivers as well as those involved in manual materials handling.

Gene_expression (found) of LBP associated with backache

7) Confidence 0.67 Published 2002 Journal Annu Rev Biomed Eng Section Abstract Doc Link 12117750 Disease Relevance 0.63 Pain Relevance 0.63

CONCLUSION: Although there is lack of causality between LBP and hip rotation, the deficit in lead leg medial hip rotation in amateur golfers who suffer LBP may be relevant for screening or treatment selection.

Gene_expression (rotation) of LBP in medial

8) Confidence 0.67 Published 2009 Journal Phys Ther Sport Section Body Doc Link 19897166 Disease Relevance 0.05 Pain Relevance 0

There was no over-representation of LBP in the groups with residual deformity, with limping or with leg length discrepancy.

Neg (no) Gene_expression (over-representation) of LBP in leg

9) Confidence 0.67 Published 1975 Journal Scand J Rehabil Med Section Abstract Doc Link 130675 Disease Relevance 0.16 Pain Relevance 0.07

AIMS: To establish LBP prevalence, beliefs regarding LBP, perceived LBP risk factors, related health service utilization, awareness and participation in manual-handling training among farmers in Ireland.

Gene_expression (prevalence) of LBP

10) Confidence 0.67 Published 2009 Journal Occup Med (Lond) Section Body Doc Link 19073993 Disease Relevance 0 Pain Relevance 0

A number of different organic syndromes were identified and the importance of psychological influences on the clinical presentation of LBP was demonstrated.

Gene_expression (presentation) of LBP associated with syndrome and backache

11) Confidence 0.67 Published 1991 Journal J Clin Epidemiol Section Abstract Doc Link 1834806 Disease Relevance 0.79 Pain Relevance 0.73

RESULTS: In the UC group (n = 163), the multivariable model included a shorter duration of the LBP episode, few previous episodes, less pain catastrophizing, and good perceived general health.

Gene_expression (duration) of LBP

12) Confidence 0.66 Published 2006 Journal Spine Section Body Doc Link 16816766 Disease Relevance 0 Pain Relevance 0

The current episode was the first ever experience of LBP in 24% of subjects, while over half (55%) had been troubled by episode(s) of LBP for ?

Gene_expression (experience) of LBP associated with backache

13) Confidence 0.66 Published 2007 Journal Chiropr Osteopat Section Body Doc Link PMC1852566 Disease Relevance 0.48 Pain Relevance 0.48

Of these 969 individuals, 524 (54%) experienced LBP in the previous 12 months, with a modal frequency of three or more times a year.

Gene_expression (experienced) of LBP

14) Confidence 0.66 Published 2004 Journal N. Z. Med. J. Section Body Doc Link 15477923 Disease Relevance 0.08 Pain Relevance 0

METHODS: French-speaking compensated workers on sick leave because of subacute common LBP (N=439) completed a questionnaire including the adapted stress process model's factors: life events and appraisal, cognitive appraisal of LBP, emotional distress, avoidance coping strategies, and functional disability.

Gene_expression (appraisal) of LBP

15) Confidence 0.66 Published 2010 Journal Spine Section Body Doc Link 20461038 Disease Relevance 0 Pain Relevance 0

Patients with greater non-LBP expenses were likelier to have been prescribed psychiatric medications.

Gene_expression (expenses) of LBP

16) Confidence 0.64 Published 2010 Journal Spine Section Body Doc Link 20228698 Disease Relevance 0 Pain Relevance 0

This increase persisted even after the following conservative adjustments: (a) excluding all radiology expenses that occurred coincident with LBP; (b) excluding billings for non-LBP conditions that occurred on days of any LBP visit because these charges may have reflected mere convenience "shopping or servicing" behavior; (c) excluding patients with a baseline of low healthcare utilization before LBP initiation because convenience may have been especially important for this cohort.

Gene_expression (conditions) of LBP in mere

17) Confidence 0.64 Published 2010 Journal Spine Section Body Doc Link 20228698 Disease Relevance 0.05 Pain Relevance 0

It may be vital to examine the health status of cooks in relation to their workplace conditions because it is reported that these conditions could cause not only LBP but also complaints in the neck, shoulders, and arms [18].

Gene_expression (cause) of LBP in arms associated with backache

18) Confidence 0.64 Published 2007 Journal BMC Public Health Section Body Doc Link PMC1971070 Disease Relevance 1.38 Pain Relevance 0.81

Separate ratings will be collected for LBP and leg pain.

Gene_expression (pain) of LBP in leg associated with pain

19) Confidence 0.60 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2874768 Disease Relevance 0.85 Pain Relevance 0.85

No direct relation between sacralization, partial or complete, and LBP was found; this was based on interrelation of the LBP and control groups, with or without sacralization, to age, ethnic community, occupation, number of changes of occupation or place of employment, duration of LBP, and physical occupational requirements (sitting, standing, bending, sudden maximal effort).

Gene_expression (found) of LBP

20) Confidence 0.60 Published 1978 Journal Scand J Rehabil Med Section Abstract Doc Link 151915 Disease Relevance 0.15 Pain Relevance 0.07

General Comments

This test has worked.