INT102718

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Context Info
Confidence 0.43
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.83
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PDPK1) nucleoplasm (PDPK1) cytoplasmic membrane-bounded vesicle (PDPK1)
plasma membrane (PDPK1) nucleus (PDPK1) kinase activity (PDPK1)
PDPK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 77.88 Quite High
Disease Link Frequency Relevance Heat
Colon Cancer 2 95.12 Very High Very High Very High
Apoptosis 3 94.32 High High
Familial Adenomatous Polyposis 1 92.40 High High
Polyps 1 90.48 High High
Cancer 1 83.92 Quite High
Death 1 81.12 Quite High
INFLAMMATION 1 77.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This effect was correlated with inhibition of the phosphorylation of the PDK1 downstream substrate Akt/protein kinase B (PKB) on two regulatory sites, Thr(308) and Ser(473).
Negative_regulation (inhibition) of Phosphorylation (phosphorylation) of PDK1
1) Confidence 0.43 Published 2002 Journal J. Biol. Chem. Section Abstract Doc Link 12000750 Disease Relevance 0.83 Pain Relevance 0.08

General Comments

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