INT102738

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.36
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.65
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
platelet 3
Atp9b (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 2 95.92 Very High Very High Very High
Percutaneous transluminal coronary angioplasty 3 92.56 High High
imagery 60 90.36 High High
antagonist 6 83.12 Quite High
Angina 3 74.36 Quite High
cva 11 56.64 Quite High
aspirin 2 35.12 Quite Low
Inflammation 38 10.96 Low Low
cytokine 12 5.00 Very Low Very Low Very Low
chemokine 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thrombosis 22 96.80 Very High Very High Very High
Cardiovascular Disease 20 91.96 High High
Vasculitis 4 88.52 High High
Thrombosis Related Under Development 1 85.84 High High
Stroke 10 75.20 Quite High
Carotid Stenosis 1 75.04 Quite High
Cv General 3 Under Development 10 74.36 Quite High
Myocardial Infarction 9 73.68 Quite High
Injury 4 70.48 Quite High
Pulmonary Embolism 3 57.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
High affinity ligand binding to alphaIIb/beta3 triggers outside-in signaling, causing microskeletal contraction and platelet retraction.
IIb Binding (binding) of in platelet
1) Confidence 0.36 Published 2002 Journal Crit. Care Med. Section Abstract Doc Link 12004256 Disease Relevance 0.37 Pain Relevance 0.20
The ensuing inside-out signaling increases several-fold the affinity and avidity of alphaIIb/beta3 for its ligands.
IIb Binding (affinity) of
2) Confidence 0.36 Published 2002 Journal Crit. Care Med. Section Abstract Doc Link 12004256 Disease Relevance 0.38 Pain Relevance 0.20
99mTc-apcitide (also known as 99mTc-P280) is a radiolabelled peptide that binds with high affinity and specificity to the GP IIb/IIIa receptors expressed on the activated platelets that are involved in acute thrombosis [151].
IIb Binding (binds) of in platelets associated with thrombosis
3) Confidence 0.36 Published 2010 Journal Eur J Nucl Med Mol Imaging Section Body Doc Link PMC2975909 Disease Relevance 0.73 Pain Relevance 0.16
A murine monoclonal antibody that binds to and blocks the IIb/IIIa receptor inhibits the binding of fibrinogen to platelets and thus inhibits platelet aggregation.
IIb Binding (binds) of in platelet
4) Confidence 0.35 Published 1998 Journal BioDrugs Section Abstract Doc Link 18020584 Disease Relevance 0.18 Pain Relevance 0.12

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox