INT102793

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Context Info
Confidence 0.33
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Egr1) intracellular (Egr1) DNA binding (Egr1)
transcription factor binding (Egr1) cytoplasm (Egr1)
Anatomy Link Frequency
neurons 2
Egr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 1 99.72 Very High Very High Very High
medulla 1 75.00 Quite High
parabrachial 1 59.04 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Following electrical intracochlear stimulation with a cochlear implant under urethane anesthesia, we observed changes in the phosphorylation state of the cAMP response element binding protein (CREB) and the expression of the immediate-early genes c-fos and egr-1, molecules known to act as transcription factors, in a tonotopically precise pattern in central auditory neurons.
Regulation (changes) of Phosphorylation (phosphorylation) of egr-1 in neurons associated with anesthesia
1) Confidence 0.33 Published 2002 Journal Exp. Neurol. Section Abstract Doc Link 12009775 Disease Relevance 0 Pain Relevance 0.17

General Comments

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