INT102844

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Context Info
Confidence 0.03
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pdc, Akt1) cytosol (Pdc, Akt1) nucleus (Pdc, Akt1)
transport (Akt1) aging (Akt1) enzyme binding (Akt1)
Anatomy Link Frequency
retina 2
Pdc (Mus musculus)
Akt1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 6 75.00 Quite High
antinociception 4 60.24 Quite High
Morphine 10 58.08 Quite High
Enkephalin 4 54.64 Quite High
Clonidine 2 46.96 Quite Low
tail-flick 2 45.60 Quite Low
Intracerebroventricular 2 40.40 Quite Low
Analgesic 2 37.44 Quite Low
tolerance 4 33.76 Quite Low
narcan 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 6 42.48 Quite Low
Urological Neuroanatomy 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Phosducin (Phd), a protein that in retina regulates rhodopsin desensitization by controlling the activity of Gt beta gamma-dependent G-protein-coupled receptor kinases (GRKs), is present in very low levels in the CNS of mammals.
Phd Regulation (controlling) of kinases in retina
1) Confidence 0.03 Published 2002 Journal Neuropharmacology Section Abstract Doc Link 12015208 Disease Relevance 0 Pain Relevance 0.25
Phosducin (Phd), a protein that in retina regulates rhodopsin desensitization by controlling the activity of Gt beta gamma-dependent G-protein-coupled receptor kinases (GRKs), is present in very low levels in the CNS of mammals.
Phosducin Regulation (controlling) of kinases in retina
2) Confidence 0.01 Published 2002 Journal Neuropharmacology Section Abstract Doc Link 12015208 Disease Relevance 0 Pain Relevance 0.25

General Comments

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