INT102853

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Context Info
Confidence 0.61
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.17
Pain Relevance 1.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Srgn) extracellular region (Srgn) Golgi apparatus (Srgn)
Anatomy Link Frequency
hippocampus 3
cerebellum 1
Srgn (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 8 99.90 Very High Very High Very High
Hippocampus 6 96.16 Very High Very High Very High
narcan 2 86.60 High High
Morphine 8 85.36 High High
addiction 2 83.00 Quite High
Disease Link Frequency Relevance Heat
Morphine Dependence 2 83.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the striatum and cerebral cortex the sGC activities and phosphorylation levels in vitro were significantly increased and were inhibited by PKA inhibitor. (3) The PDE activities showed no change in cerebellum and hippocampus, but in striatum and cerebral cortex PDE activities and phosphorylation levels in vitro were significantly increased and were inhibited by PKA inhibitor. (4) These changes described above were not observed in mice treated with naloxone 30 min prior to daily morphine injection.
Positive_regulation (increased) of Phosphorylation (phosphorylation) of sGC in hippocampus associated with narcan, hippocampus, cerebral cortex and morphine
1) Confidence 0.61 Published 1998 Journal Yao Xue Xue Bao Section Abstract Doc Link 12016853 Disease Relevance 0.08 Pain Relevance 0.66
In the striatum and cerebral cortex the sGC activities and phosphorylation levels in vitro were significantly increased and were inhibited by PKA inhibitor. (3) The PDE activities showed no change in cerebellum and hippocampus, but in striatum and cerebral cortex PDE activities and phosphorylation levels in vitro were significantly increased and were inhibited by PKA inhibitor. (4) These changes described above were not observed in mice treated with naloxone 30 min prior to daily morphine injection.
Positive_regulation (increased) of in cerebellum Phosphorylation (phosphorylation) of sGC in hippocampus associated with narcan, hippocampus, cerebral cortex and morphine
2) Confidence 0.21 Published 1998 Journal Yao Xue Xue Bao Section Abstract Doc Link 12016853 Disease Relevance 0.08 Pain Relevance 0.66

General Comments

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