INT102862

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Context Info
Confidence 0.19
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Prkaca, Twist1) cell differentiation (Twist1) mitochondrion (Prkaca)
Golgi apparatus (Prkaca) DNA binding (Twist1) protein complex (Prkaca)
Prkaca (Mus musculus)
Twist1 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 1 98.82 Very High Very High Very High
Morphine 4 98.60 Very High Very High Very High
Hippocampus 3 93.68 High High
cerebral cortex 4 92.40 High High
narcan 1 46.56 Quite Low
Disease Link Frequency Relevance Heat
Morphine Dependence 1 98.82 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By inducing morphine dependence in mice, the changes of cGMP contents, phosphodiesterase (PDE) and soluble guanylate cyclase (sGC) activities and their phosphorylation regulated by protein kinase A (PKA) were observed.
PKA Regulation (regulated) of Phosphorylation (phosphorylation) of PDE associated with addiction and morphine
1) Confidence 0.19 Published 1998 Journal Yao Xue Xue Bao Section Abstract Doc Link 12016853 Disease Relevance 0.10 Pain Relevance 0.42

General Comments

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