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Context Info
Confidence 0.14
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ADRBK2, ADRBK1) plasma membrane (ADRBK1, OPRK1) cytosol (ADRBK1)
aging (ADRBK1) signal transducer activity (OPRK1) cytoplasm (ADRBK1)
ADRBK2 (Homo sapiens)
ADRBK1 (Homo sapiens)
OPRK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 76.16 Quite High
Kappa opioid receptor 3 75.00 Quite High
Opioid 1 68.12 Quite High
opioid receptor 1 30.76 Quite Low


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Comparing the effect of over-expressed GRK2 and GRK3 on sequestration of kappa-receptors, we conclude that GRK3 more strongly induces kappa-receptor internalization than GRK2.
GRK3 Positive_regulation (induces) of GRK2 Binding (internalization) of kappa-receptor
1) Confidence 0.14 Published 2002 Journal Mol. Pharmacol. Section Abstract Doc Link 12021406 Disease Relevance 0 Pain Relevance 0.14

General Comments

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