INT102992

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Context Info
Confidence 0.60
First Reported 2002
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.59
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SRD5A1) small molecule metabolic process (SRD5A1) endoplasmic reticulum (SRD5A1)
cytoplasm (SRD5A1)
SRD5A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 36 100.00 Very High Very High Very High
Onset of action 2 41.36 Quite Low
c fibre 1 29.28 Quite Low
Central nervous system 2 25.00 Low Low
Inflammation 11 5.00 Very Low Very Low Very Low
cINOD 7 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Overactive Bladder 229 99.84 Very High Very High Very High
Benign Prostatic Hypertrophy 248 99.08 Very High Very High Very High
Hematuria 11 97.96 Very High Very High Very High
Reprotox - General 1 18 97.84 Very High Very High Very High
Lower Urinary Tract Symptoms 85 93.28 High High
Pressure Volume 2 Under Development 5 85.96 High High
Dizziness 3 84.96 Quite High
Gynecomastia 4 54.80 Quite High
Disease 17 50.00 Quite Low
Stress Incontinence 8 27.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Role of 5-alpha reductase inhibitors in AUR
Regulation (Role) of Negative_regulation (inhibitors) of 5-alpha reductase associated with overactive bladder
1) Confidence 0.60 Published 2007 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2721562 Disease Relevance 1.26 Pain Relevance 0
Theoretically, there seem to be several possibilities to improve the current treatment, which is based mainly on alpha1-adrenoceptor (AR) antagonists, 5alpha-reductase inhibitors and phytotherapy.
Regulation (based) of Negative_regulation (inhibitors) of 5alpha-reductase associated with antagonist
2) Confidence 0.44 Published 2002 Journal World J Urol Section Abstract Doc Link 12022712 Disease Relevance 0.54 Pain Relevance 0.24
The role of 5-alpha-reductase inhibitors
Regulation (role) of Negative_regulation (inhibitors) of 5-alpha-reductase
3) Confidence 0.44 Published 2008 Journal International Journal of Clinical Practice Section Body Doc Link PMC2440415 Disease Relevance 0.81 Pain Relevance 0
Recent studies demonstrate that 5-alpha-reductase inhibitors are effective in the treatment of BPH-induced hematuria,41 probably through their effect on prostate microvessel density.42 Multiple studies now support the role of short-term 5-alpha-reductase inhibitor monotherapy prior to definitive surgical resection in order to decrease hematuria during and after the procedure.43,44

5-alpha-reductase inhibitor and alpha-adrenergic receptor antagonist combination therapy

Regulation (role) of Negative_regulation (inhibitor) of 5-alpha-reductase associated with benign prostatic hypertrophy, antagonist and hematuria
4) Confidence 0.44 Published 2009 Journal Patient Prefer Adherence Section Body Doc Link PMC2778433 Disease Relevance 0.99 Pain Relevance 0.05

General Comments

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