INT103022

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Context Info
Confidence 0.44
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.52
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Slc6a4) endosome (Slc6a4) transport (Slc6a4)
plasma membrane (Slc6a4)
Slc6a4 (Mus musculus)
Pain Link Frequency Relevance Heat
fluoxetine 11 97.64 Very High Very High Very High
Serotonin 36 76.36 Quite High
Raphe 4 5.00 Very Low Very Low Very Low
monoamine 2 5.00 Very Low Very Low Very Low
primary somatosensory cortex 1 5.00 Very Low Very Low Very Low
Thalamus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 5 99.98 Very High Very High Very High
Pressure And Volume Under Development 1 82.20 Quite High
Hypertension 4 75.00 Quite High
Targeted Disruption 1 52.48 Quite High
Increased Venous Pressure Under Development 1 37.12 Quite Low
Handedness 12 5.00 Very Low Very Low Very Low
Ganglion Cysts 3 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low
Vibrio Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a recent study, we showed that hypoxia increases the rate of 5-HTT gene transcription in PASMCs and potentiates the growth-promoting effect of 5-HT on these cells.
Positive_regulation (increases) of Transcription (transcription) of 5-HTT gene associated with hypoxia
1) Confidence 0.44 Published 2002 Journal J. Lab. Clin. Med. Section Abstract Doc Link 12024106 Disease Relevance 0.52 Pain Relevance 0.21
To determine if Sert is a direct transcriptional target of Zic2, we investigated whether this transcription factor activates Sert regulatory sequences.
Positive_regulation (activates) of Transcription (transcription) of Sert
2) Confidence 0.42 Published 2010 Journal EMBO J Section Body Doc Link PMC2944059 Disease Relevance 0 Pain Relevance 0

General Comments

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