INT10303

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Context Info
Confidence 0.60
First Reported 1982
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 16
Total Number 17
Disease Relevance 16.14
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (STH) cytoplasm (STH)
Anatomy Link Frequency
blood 1
plasma 1
STH (Homo sapiens)
Pain Link Frequency Relevance Heat
Cholecystokinin 1 98.76 Very High Very High Very High
Opioid 1 98.08 Very High Very High Very High
Dismenorea 2 96.76 Very High Very High Very High
Chronic pancreatitis 3 95.96 Very High Very High Very High
headache 17 88.04 High High
Inflammatory response 6 84.88 Quite High
Pain 3 70.64 Quite High
pruritus 3 38.08 Quite Low
Angina 1 15.44 Low Low
abdominal pain 15 6.48 Low Low
Disease Link Frequency Relevance Heat
Helminth Infection 191 100.00 Very High Very High Very High
Lymphatic Filariasis 186 100.00 Very High Very High Very High
Schistosomiasis 172 100.00 Very High Very High Very High
Infection 286 99.96 Very High Very High Very High
Conjunctivitis 50 99.76 Very High Very High Very High
Reprotox - General 1 6 99.76 Very High Very High Very High
Disease 337 99.02 Very High Very High Very High
Syndrome 17 99.00 Very High Very High Very High
Onchocerciasis 89 98.44 Very High Very High Very High
Eye Infections 3 97.28 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of parlodel acute load on STH and the blood serum prolactin content was studied.
Regulation (effect) of STH in blood
1) Confidence 0.60 Published 1983 Journal Probl Endokrinol (Mosk) Section Abstract Doc Link 6682222 Disease Relevance 0.66 Pain Relevance 0.10
[Effect of acute parlodel load on the prolactin and STH content in patients with various neuroendocrine diseases].
Regulation ([Effect) of STH associated with disease
2) Confidence 0.44 Published 1983 Journal Probl Endokrinol (Mosk) Section Title Doc Link 6682222 Disease Relevance 0.64 Pain Relevance 0.09
Estimation of at-risk populations for schistosomiasis and STH
Regulation (populations) of STH associated with helminth infection and schistosomiasis
3) Confidence 0.39 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2990690 Disease Relevance 0.52 Pain Relevance 0
Despite the high burden of these diseases in the country, there has never been a national control program on schistosomiasis and STH.
Regulation (control) of STH associated with helminth infection, disease and schistosomiasis
4) Confidence 0.39 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2990690 Disease Relevance 1.74 Pain Relevance 0
The responses of gonadotropins, TSH, somatotropin (STH) and prolactin (PRL) were studied in the group as a whole and in clinical subgroups.
Regulation (responses) of STH
5) Confidence 0.26 Published 1982 Journal Headache Section Abstract Doc Link 17152744 Disease Relevance 0.23 Pain Relevance 0.16
Therefore, an important aspect to be considered once the PELF campaigns terminate is how to maintain the benefit of control of STH obtained by the distribution of albendazole.
Regulation (control) of STH associated with lymphatic filariasis
6) Confidence 0.26 Published 2008 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2565698 Disease Relevance 0.53 Pain Relevance 0
Whereas under the onchocerciasis programme, which only delivers ivermectin (ivermectin is not recommended for STH control due to its suboptimal effect against the STH parasites [9]), the simultaneous distribution of albendazole for STH deworming could be considered, which would take advantage of the established onchocerciasis delivery channel.
Regulation (control) of STH associated with onchocerciasis
7) Confidence 0.15 Published 2008 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2274864 Disease Relevance 0.75 Pain Relevance 0
No correlation was discovered between alterations in the STH level and the activity of pancreatic enzymes.
Regulation (alterations) of STH
8) Confidence 0.14 Published 1986 Journal Ter. Arkh. Section Abstract Doc Link 3518116 Disease Relevance 0.52 Pain Relevance 0.27
Whereas under the onchocerciasis programme, which only delivers ivermectin (ivermectin is not recommended for STH control due to its suboptimal effect against the STH parasites [9]), the simultaneous distribution of albendazole for STH deworming could be considered, which would take advantage of the established onchocerciasis delivery channel.
Regulation (effect) of STH associated with onchocerciasis
9) Confidence 0.11 Published 2008 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2274864 Disease Relevance 0.75 Pain Relevance 0
Similarly, co-administration of praziquantel and albendazole is an efficacious and safe tool to control morbidity due to schistosomiasis and STH in areas where both infections are endemic [24].
Regulation (control) of STH associated with helminth infection, infection and schistosomiasis
10) Confidence 0.07 Published 2008 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2217668 Disease Relevance 1.52 Pain Relevance 0.11
The drawback of community-based interventions for both lymphatic filariasis and onchocerciasis is that they usually take place once a year, which may not be sufficient to effectively control STH infection in high-risk communities where two yearly distributions are recommended [9].
Regulation (control) of STH associated with onchocerciasis, lymphatic filariasis and infection
11) Confidence 0.06 Published 2008 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2274864 Disease Relevance 0.74 Pain Relevance 0
Model experiments with primary monolayer cultures of isolated islet cells have helped demonstrate a direct insulinotropic effect of STH, TRH, C-terminal tetrapeptide cholecystokinin, opioid peptides and blood plasma of patients with insulin-dependent diabetes mellitus.
Regulation (effect) of STH in plasma associated with diabetes mellitus, opioid and cholecystokinin
12) Confidence 0.05 Published 1992 Journal Probl Endokrinol (Mosk) Section Abstract Doc Link 1480583 Disease Relevance 0.31 Pain Relevance 0.15
Children Without Worms (CWW) was established as a partnership between Johnson & Johnson and the Task Force for Global Health to leverage the donation of mebendazole from Johnson & Johnson to advocate for comprehensive and sustainable control of STH with a focus exclusively on school-age children http://www.childrenwithoutworms.org.
Regulation (control) of STH associated with helminth infection
13) Confidence 0.04 Published 2010 Journal BMC Med Section Body Doc Link PMC2987894 Disease Relevance 1.54 Pain Relevance 0
Generally, control of STH is integrated into other programmes such as nutrition or school health as a deworming component, and is often part of schistosomiasis control programmes or as a collateral benefit from LF control programmes, as the same drug is used.
Regulation (control) of STH associated with helminth infection, lymphatic filariasis and schistosomiasis
14) Confidence 0.04 Published 2010 Journal BMC Med Section Body Doc Link PMC2987894 Disease Relevance 1.36 Pain Relevance 0
As for schistosomiasis control, only a few countries are currently implementing or about to implement national integrated NTD control programmes that include STH control.


Regulation (control) of STH associated with helminth infection and schistosomiasis
15) Confidence 0.04 Published 2010 Journal BMC Med Section Body Doc Link PMC2987894 Disease Relevance 1.63 Pain Relevance 0.07
Control of schistosomiasis and STH through large-scale preventive chemotherapy interventions distributing praziquantel and albendazole started in 1994.
Regulation (Control) of STH associated with helminth infection and schistosomiasis
16) Confidence 0.04 Published 2008 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2217668 Disease Relevance 1.14 Pain Relevance 0
Control of LF, STH and Schistosomiasis in Zanzibar
Regulation (Control) of STH associated with helminth infection, lymphatic filariasis and schistosomiasis
17) Confidence 0.04 Published 2008 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2217668 Disease Relevance 1.49 Pain Relevance 0

General Comments

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