INT103031

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Context Info
Confidence 0.46
First Reported 2002
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.98
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Calca, Ptgs1) cytoplasm (Calca, Ptgs1) nucleus (Calca, Ptgs1)
nuclear envelope (Ptgs1) Golgi apparatus (Ptgs1) endoplasmic reticulum (Ptgs1)
Anatomy Link Frequency
sensory neuron 1
Calca (Rattus norvegicus)
Ptgs1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 16 100.00 Very High Very High Very High
qutenza 13 96.64 Very High Very High Very High
Inflammatory response 2 93.84 High High
Root ganglion neuron 1 87.88 High High
antagonist 3 78.56 Quite High
ischemia 5 75.00 Quite High
cOX1 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Injury 11 98.92 Very High Very High Very High
INFLAMMATION 2 93.48 High High
Ganglion Cysts 1 87.56 High High
Cv Unclassified Under Development 5 75.00 Quite High
Necrosis 1 47.72 Quite Low
Cancer 1 47.36 Quite Low
Nociception 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this process, CGRP-induced activation of both endothelial nitric oxide synthase and cyclooxygenase-1 might be critically involved.
CGRP Positive_regulation (activation) of cyclooxygenase-1 associated with calcitonin gene-related peptide
1) Confidence 0.46 Published 2005 Journal Thromb. Haemost. Section Abstract Doc Link 15630490 Disease Relevance 0.56 Pain Relevance 0.76
In the sensory neuron-mediated enhancement of endothelial production of prostacyclin, CGRP-induced activation of both endothelial NOS and cyclooxygenase-1 may be critically involved.
CGRP Positive_regulation (activation) of cyclooxygenase in sensory neuron associated with calcitonin gene-related peptide
2) Confidence 0.11 Published 2002 Journal J. Lab. Clin. Med. Section Abstract Doc Link 12024109 Disease Relevance 0.41 Pain Relevance 0.46

General Comments

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