INT103042

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Context Info
Confidence 0.04
First Reported 2002
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 2.09
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Myst2) nucleus (Myst2) intracellular (Myst2)
transferase activity, transferring acyl groups (Myst2)
Myst2 (Mus musculus)
Pain Link Frequency Relevance Heat
cva 9 90.44 High High
ischemia 12 54.04 Quite High
Restless leg syndrome 1 50.00 Quite Low
cytokine 36 16.76 Low Low
Inflammation 18 6.36 Low Low
Migraine 6 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parasitemia 63 100.00 Very High Very High Very High
Hypothermia 15 99.56 Very High Very High Very High
Infection 27 98.60 Very High Very High Very High
Cerebral Malaria 186 91.36 High High
Sprains And Strains 9 91.28 High High
Cv General 3 Under Development 3 90.44 High High
Cv General 4 Under Development 6 78.72 Quite High
Apoptosis 6 75.64 Quite High
Necrosis 3 71.64 Quite High
Pressure And Volume Under Development 9 70.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, since 100% of non-exposed PbA-infected mice died, we decided to evaluate whether the reduction on parasitemia levels in HBO exposed animals could be sustained over longer periods.
Negative_regulation (reduction) of HBO associated with parasitemia
1) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2518956 Disease Relevance 0.75 Pain Relevance 0
When comparing exposed animals with non-exposed animals, we noticed a significant reduction on the parasitemia levels of PbA-infected mice exposed to HBO (11-day exposure protocol) during infection (4–6 p.i.; Figure 1B).
Negative_regulation (reduction) of HBO associated with parasitemia and infection
2) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2518956 Disease Relevance 0.81 Pain Relevance 0.11
Unlike in the case of non-exposed mice, HBO therapy significantly prevented (P<0.001) hypothermia in mice from day 6 p.i., when severe neurological signs were evident in most of the animals (data not shown).
Negative_regulation (prevented) of HBO associated with hypothermia
3) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2518956 Disease Relevance 0.53 Pain Relevance 0
RESULTS: exercise was associated with a decrease in HbO(2) and an increase in Hb.
Negative_regulation (decrease) of HbO
4) Confidence 0.02 Published 2002 Journal Eur J Vasc Endovasc Surg Section Body Doc Link 12027464 Disease Relevance 0 Pain Relevance 0

General Comments

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