INT103096
From wiki-pain
|
|
|
|
|
Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Recently, Vldlr was shown to be under control of PPAR? | |||||||||||||||
| |||||||||||||||
|
The DNA response element conferring PPAR regulation was located to intron 3 of the Angptl4 gene [127]. | |||||||||||||||
| |||||||||||||||
|
the control of PPAR transcriptional activity. | |||||||||||||||
| |||||||||||||||
|
Effects of xenobiotics and peroxisome proliferator-activated receptor-alpha on the human UDPglucose dehydrogenase gene expression. | |||||||||||||||
| |||||||||||||||
|
regulation of PPAR? | |||||||||||||||
| |||||||||||||||
|
Promoter analysis of the human UGT1A3 gene revealed coregulation by two lipid-sensing transcription factors, LXR [126] and PPAR? | |||||||||||||||
| |||||||||||||||
|
Posttranslational modifications regulate PPAR? | |||||||||||||||
| |||||||||||||||
|
The effects of PPAR ligands on neuroinflammation in animal models suggest their possible use for treating human inflammatory pain and neuropathic pain. | |||||||||||||||
| |||||||||||||||
|
Other genes involved in cholesterol uptake and transport that were shown to be under control of PPAR? | |||||||||||||||
| |||||||||||||||
|
Overall, these data suggest that Vnn1 represents a direct PPAR? | |||||||||||||||
| |||||||||||||||
|
Having confirmed the bioinformatics in a multi-racial human cohort, the next step was to determine if there were any effects of the PPARA promoter SNP on transcription factor binding and transcriptional activity. | |||||||||||||||
| |||||||||||||||
|
Agents that specifically target proteins, transcription factors or ion channels, including PKC agonists/antagonists, PPAR, Phosphodiesterase-5 inhibitors, 3-Hydroxy-3-methyl glutaryl coenzyme A reductase and the ATP-dependent potassium channel are also promising. | |||||||||||||||
| |||||||||||||||
|
This study was designed to investigate the effect of fenofibrate, a PPAR-? | |||||||||||||||
| |||||||||||||||
|
Taken together, these results suggest that tissue-specific regulation of PPAR? | |||||||||||||||
| |||||||||||||||
|
suggest that anti-inflammatory effects of PPAR agonist are likely | |||||||||||||||
| |||||||||||||||
|
also been noted, suggesting a deregulation of PPAR? | |||||||||||||||
| |||||||||||||||
|
The PPAR regulation of | |||||||||||||||
| |||||||||||||||
|
The down-regulation of PPAR? | |||||||||||||||
| |||||||||||||||
|
anti-inflammatory role of this receptor, PPAR? | |||||||||||||||
| |||||||||||||||
|
dependent on PPAR? | |||||||||||||||
| |||||||||||||||
|
General Comments
This test has worked.