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Context Info
Confidence 0.07
First Reported 2002
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.43
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NFKB1) mitochondrion (NFKB1) cytoplasm (NFKB1)
cytosol (NFKB1) signal transduction (NFKB1) nucleolus (NFKB1)
DCSTAMP (Homo sapiens)
NFKB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 6 99.16 Very High Very High Very High
cytokine 7 83.44 Quite High
Inflammatory mediators 1 80.52 Quite High
endometriosis 1 77.76 Quite High
Pain 1 74.36 Quite High
Inflammation 1 26.88 Quite Low
Disease Link Frequency Relevance Heat
Skin Cancer 8 98.74 Very High Very High Very High
Endometriosis 5 94.04 High High
Cancer 2 89.64 High High
INFLAMMATION 2 80.12 Quite High
Sleep Initiation And Maintenance Disorders 1 75.08 Quite High
Pain 1 74.36 Quite High
Disease 1 73.84 Quite High
Necrosis 1 68.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Electrophoretic mobility shift assay revealed that treatment of these cultures with the urinary preparation hCG-A suppressed TNF-alpha- or IL-1beta-induced NF-kappaB DNA-binding activity, whereas another urinary hCG preparation (hCG-B) was less effective.
IL-1beta-induced Positive_regulation (induced) of NF-kappaB
1) Confidence 0.07 Published 2007 Journal Mol. Hum. Reprod. Section Abstract Doc Link 17525069 Disease Relevance 0.71 Pain Relevance 0.27
Treatment of melanoma cells with capsaicin inhibited activation of constitutive and IL-1beta-induced NF-kappaB, but not AP-1, leading to inhibition of IL-8 expression.
IL-1beta-induced Positive_regulation (induced) of NF-kappaB associated with qutenza and skin cancer
2) Confidence 0.07 Published 2002 Journal J. Interferon Cytokine Res. Section Abstract Doc Link 12034025 Disease Relevance 0.72 Pain Relevance 0.43

General Comments

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