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Context Info
Confidence 0.05
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.19
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (NF1) signal transduction (NF1) nucleus (NF1)
intracellular (NF1) extracellular matrix organization (NF1) cytoplasm (NF1)
Anatomy Link Frequency
Schwann cells 1
NF1 (Homo sapiens)
ras (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 90.40 High High
Pain 1 86.84 High High
Antihistamine 1 65.44 Quite High
Disease Link Frequency Relevance Heat
Watson Syndrome 6 99.70 Very High Very High Very High
Neurologic Manifestations 1 87.84 High High
Neurofibroma 4 87.28 High High
Pain 1 86.84 High High
Congenital Anomalies 1 86.60 High High
Plexiform Neurofibroma 5 84.52 Quite High
Disease 1 79.16 Quite High
Cancer 2 44.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There is increasing evidence that loss of NF1 expression in neoplastic Schwann cells is associated with elevated levels of activated RAS, supporting the notion that the NF1 gene product, neurofibromin, acts as a growth regulator by inhibiting ras growth-promoting activity.
neurofibromin Negative_regulation (inhibiting) of ras in Schwann cells associated with watson syndrome
1) Confidence 0.05 Published 2002 Journal Neurology Section Abstract Doc Link 12041525 Disease Relevance 1.19 Pain Relevance 0.16

General Comments

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