INT103300

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Context Info
Confidence 0.44
First Reported 2002
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.87
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CRTAC1) proteinaceous extracellular matrix (CRTAC1)
Anatomy Link Frequency
spinal 2
medulla 2
CRTAC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 1 100.00 Very High Very High Very High
medulla 1 100.00 Very High Very High Very High
substance P 1 100.00 Very High Very High Very High
Pain 5 99.56 Very High Very High Very High
Cancer pain 1 96.12 Very High Very High Very High
imagery 1 63.08 Quite High
headache 1 61.96 Quite High
Disease Link Frequency Relevance Heat
Pain 4 99.56 Very High Very High Very High
Bone Cancer 4 98.88 Very High Very High Very High
Cancer 5 97.76 Very High Very High Very High
Hypercapnia 5 96.96 Very High Very High Very High
Ganglion Cysts 1 96.72 Very High Very High Very High
Medulloblastoma 5 95.36 Very High Very High Very High
Asphyxia 6 93.20 High High
Toxicity 1 90.48 High High
Rhinitis 1 86.00 High High
Hypercalcemia 2 84.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Risedronate decreased bone cancer-related bone destruction and pain-related behavior and decreased the spinal expression of glial fibrillary acidic protein, whereas NE-10790 had no effect on these parameters.
Negative_regulation (decreased) of Gene_expression (expression) of acidic protein in spinal associated with pain and bone cancer
1) Confidence 0.44 Published 2009 Journal Int. J. Cancer Section Abstract Doc Link 19444917 Disease Relevance 1.27 Pain Relevance 0.41
Immunohistochemical staining revealed diffuse expression of synaptophysin and neurofilament protein, and focal expression of glial fibrillary acidic protein, S-100 protein, desmin, and myoglobin.
Negative_regulation (revealed) of Gene_expression (expression) of acidic protein
2) Confidence 0.00 Published 2008 Journal Brain Tumor Pathol Section Abstract Doc Link 18415665 Disease Relevance 0.73 Pain Relevance 0.09
The immunoreactive expression of glial fibrillary acidic protein, tyrosine hydroxylase, substance P and met-enkephalin in the medulla was also not different between the three groups.
Neg (not) Negative_regulation (different) of Gene_expression (expression) of acidic protein in medulla associated with medulla, enkephalin and substance p
3) Confidence 0.00 Published 2002 Journal Reprod. Fertil. Dev. Section Abstract Doc Link 12051528 Disease Relevance 0.88 Pain Relevance 0.20

General Comments

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