INT103391

Context Info Confidence 0.01 First Reported 2002 Last Reported 2002 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.88 Pain Relevance 0.32

cell differentiation (SLC9A1) mitochondrion (Nfkb1) DNA binding (Nfkb1) protein complex (Nfkb1) cytoplasm (Nfkb1) transmembrane transport (SLC9A1)

SLC9A1 (Homo sapiens) Nfkb1 (Mus musculus)

Pain Link Frequency Relevance Heat Clonidine 1 93.28 Inflammation 3 81.36 Inflammatory response 3 78.64

Disease Link Frequency Relevance Heat Inflammatory Bowel Disease 5 95.84 Disease 1 84.52 Mucositis 1 80.72 INFLAMMATION 4 78.28 Colitis 1 75.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

NHE inhibition suppressed both activation of the p42/p44 mitogen-activated protein kinase and nuclear factor-kappaB.

Negative_regulation (inhibition) of NHE Negative_regulation (suppressed) of Positive_regulation (activation) of nuclear factor-kappaB

1) Confidence 0.01 Published 2002 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 12065299 Disease Relevance 0.88 Pain Relevance 0.32

General Comments

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