INT10340

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Context Info
Confidence 0.60
First Reported 1983
Last Reported 2006
Negated 6
Speculated 5
Reported most in Abstract
Documents 30
Total Number 35
Disease Relevance 2.55
Pain Relevance 14.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Oxt) extracellular region (Oxt) cytoplasm (Oxt)
Anatomy Link Frequency
plasma 4
spinal cord 4
neurohypophysis 4
uterine 2
nucleus 2
Oxt (Mus musculus)
Pain Link Frequency Relevance Heat
narcan 52 100.00 Very High Very High Very High
Morphine 33 100.00 Very High Very High Very High
Opioid 29 100.00 Very High Very High Very High
opiate 14 100.00 Very High Very High Very High
epidural 11 100.00 Very High Very High Very High
antagonist 10 100.00 Very High Very High Very High
analgesia 9 100.00 Very High Very High Very High
Intracerebroventricular 8 100.00 Very High Very High Very High
Endogenous opioid 7 100.00 Very High Very High Very High
intrathecal fentanyl 4 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Stress 13 99.92 Very High Very High Very High
Dysmenorrhea 19 98.80 Very High Very High Very High
Pain 3 96.44 Very High Very High Very High
Hemorrhage 2 93.52 High High
Peripheral Arterial Disease 1 86.24 High High
Anxiety Disorder 3 84.08 Quite High
Heart Rate Under Development 1 82.00 Quite High
Hypoventilation 1 80.32 Quite High
Poisoning 1 66.64 Quite High
Aids-related Complex 1 62.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of epidural analgesia on oxytocin release during the second stage of normal labour was studied by comparing 10 primigravidae who had epidurals with 10 control subjects who did not have epidurals.
Regulation (effect) of Localization (release) of oxytocin associated with epidural and analgesia
1) Confidence 0.60 Published 1983 Journal Br J Obstet Gynaecol Section Abstract Doc Link 6830729 Disease Relevance 0 Pain Relevance 0.36
To test the hypothesis that oxytocin secretion is regulated by endogenous opioids in the periparturient period, we have 1) characterized oxytocin secretion in response to vaginocervical stimulation and 2) determined the effect of naloxone, an opioid antagonist, on oxytocin secretion induced by vaginocervical stimulation in prepartum mares and in postpartum mares at estrus and diestrus.
Regulation (regulated) of Localization (secretion) of oxytocin associated with antagonist, narcan, endogenous opioid and opioid
2) Confidence 0.60 Published 1996 Journal Theriogenology Section Abstract Doc Link 16727907 Disease Relevance 0 Pain Relevance 0.31
We studied the effects of spinal intrathecal fentanyl on oxytocin secretion in 20 healthy women prior to an elective caesarean delivery at term under spinal anaesthesia.
Regulation (effects) of Localization (secretion) of oxytocin in spinal associated with intrathecal fentanyl
3) Confidence 0.60 Published 2001 Journal Clin. Sci. Section Abstract Doc Link 11566079 Disease Relevance 0 Pain Relevance 0.28
Effect of intrathecal fentanyl on oxytocin secretion in pregnant women not in labour.
Regulation (Effect) of Neg (not) Localization (secretion) of oxytocin associated with intrathecal fentanyl
4) Confidence 0.60 Published 2001 Journal Clin. Sci. Section Title Doc Link 11566079 Disease Relevance 0 Pain Relevance 0.41
The role of endogenous opiates in the control of the secretion of oxytocin in the basal state in healthy male volunteers was investigated with the opiate antagonist naloxone.
Regulation (control) of Localization (secretion) of oxytocin associated with antagonist, narcan and opiate
5) Confidence 0.55 Published 1986 Journal Psychoneuroendocrinology Section Abstract Doc Link 3749403 Disease Relevance 0 Pain Relevance 0.56
Nine multiparous cyclic sows with permanent jugular catheters were introduced to a boar at day 10 (n = 9) or 11 (n = 5) after ovulation to study the effect on oxytocin (OT) release.
Regulation (effect) of Localization (release) of oxytocin
6) Confidence 0.53 Published 2006 Journal Reprod. Domest. Anim. Section Abstract Doc Link 16689888 Disease Relevance 0.09 Pain Relevance 0.09
Opioid modulation of oxytocin release from spinal cord synaptosomes.
Regulation (modulation) of Localization (release) of oxytocin in spinal cord associated with opioid and spinal cord
7) Confidence 0.47 Published 1994 Journal Neuroreport Section Title Doc Link 7827343 Disease Relevance 0 Pain Relevance 0.97
Regulation of oxytocin release from spinal cord synaptosomes was investigated using in vitro preparations.
Regulation (Regulation) of Localization (release) of oxytocin in spinal cord associated with spinal cord
8) Confidence 0.47 Published 1994 Journal Neuroreport Section Abstract Doc Link 7827343 Disease Relevance 0 Pain Relevance 0.39
Experiments were designed to determine whether opioid peptides regulate oxytocin release from spinal cord synaptosomes, as they do from synaptosomes derived from neurohypophysis.
Spec (whether) Regulation (regulate) of Localization (release) of oxytocin in neurohypophysis associated with opioid and spinal cord
9) Confidence 0.47 Published 1994 Journal Neuroreport Section Abstract Doc Link 7827343 Disease Relevance 0 Pain Relevance 0.51
To test the hypothesis that oxytocin secretion is regulated by endogenous opioids in the periparturient period, we have 1) characterized oxytocin secretion in response to vaginocervical stimulation and 2) determined the effect of naloxone, an opioid antagonist, on oxytocin secretion induced by vaginocervical stimulation in prepartum mares and in postpartum mares at estrus and diestrus.
Spec (determined) Regulation (effect) of Localization (secretion) of oxytocin associated with antagonist, narcan, endogenous opioid and opioid
10) Confidence 0.44 Published 1996 Journal Theriogenology Section Abstract Doc Link 16727907 Disease Relevance 0 Pain Relevance 0.34
Evidence for the effects of synthetic boar odor on oxytocin release and/or uterine activity is inconsistent.
Regulation (effects) of Localization (release) of oxytocin in uterine
11) Confidence 0.44 Published 2005 Journal Theriogenology Section Abstract Doc Link 15626413 Disease Relevance 0.26 Pain Relevance 0.26
Oxytocin secretion in response to either novel environment or forced swimming was unchanged in any reproductive group, whereas vasopressin secretion was decreased by both stressors, but only in virgins.
Neg (unchanged) Regulation (unchanged) of Localization (secretion) of Oxytocin
12) Confidence 0.42 Published 2003 Journal Endocrinology Section Abstract Doc Link 12960085 Disease Relevance 0.49 Pain Relevance 0.29
Effects of lumbar epidural analgesia on prostaglandin F2 alpha release and oxytocin secretion during labor.
Regulation (Effects) of Localization (secretion) of oxytocin associated with epidural and analgesia
13) Confidence 0.39 Published 1993 Journal Prostaglandins Section Title Doc Link 8484013 Disease Relevance 0 Pain Relevance 0.77
The role of oxytocin release in the paraventricular nucleus in the control of maternal behaviour in the sheep.
Regulation (role) of Localization (release) of oxytocin in nucleus
14) Confidence 0.35 Published 1996 Journal J. Neuroendocrinol. Section Title Doc Link 8730650 Disease Relevance 0 Pain Relevance 0
Physiological regulation of maternal behavior in heifers: roles of genital stimulation, intracerebral oxytocin release, and ovarian steroids.
Regulation (regulation) of Localization (release) of oxytocin
15) Confidence 0.34 Published 2001 Journal Biol. Reprod. Section Title Doc Link 11420252 Disease Relevance 0 Pain Relevance 0.38
No treatment influenced oxytocin release per se, but i.c.v. morphine increased both peripheral and central release of oxytocin in response to vaginocervical stimulation.
Neg (No) Regulation (influenced) of Localization (release) of oxytocin associated with morphine
16) Confidence 0.34 Published 1991 Journal Brain Res. Section Abstract Doc Link 2054633 Disease Relevance 0 Pain Relevance 0.75
OBJECTIVE: Modification of the inhibitory control of oxytocin secretion by endogenous opiates in late pregnancy may be one of the factors involved in the onset of labour.
Regulation (control) of Localization (secretion) of oxytocin associated with opiate
17) Confidence 0.30 Published 1993 Journal Clin. Endocrinol. (Oxf) Section Abstract Doc Link 8287585 Disease Relevance 0 Pain Relevance 0.49
The activity of opiate-mediated regulatory mechanisms of oxytocin secretion during breast-feeding was studied by the administration of either morphine, naloxone or placebo to women prior to the commencement of breast-feeding.
Regulation (regulatory) of Localization (secretion) of oxytocin associated with narcan, opiate and morphine
18) Confidence 0.27 Published 1999 Journal Gynecol. Obstet. Invest. Section Abstract Doc Link 10394089 Disease Relevance 0 Pain Relevance 0.44
OBJECTIVE: We investigated the effect of an opiate (morphine) and an opiate antagonist (naloxone) on the maternal secretion of oxytocin in the first stage of labour.
Spec (investigated) Regulation (effect) of Localization (secretion) of oxytocin associated with antagonist, narcan, opiate and morphine
19) Confidence 0.27 Published 1992 Journal Clin. Endocrinol. (Oxf) Section Abstract Doc Link 1483291 Disease Relevance 0 Pain Relevance 0.51
OxyContin (oxycodone hydrochloride controlled release) is a long-acting preparation of oxycodone that is used as an opioid analgesic to treat chronic pain conditions.
Regulation (controlled) of Localization (release) of OxyContin associated with oxycodone, lasting pain, analgesic and opioid
20) Confidence 0.26 Published 2002 Journal Ann Emerg Med Section Abstract Doc Link 12239500 Disease Relevance 0.33 Pain Relevance 0.63

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