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Context Info
Confidence 0.03
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.26

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cytosol (Gria1) extracellular region (BDNF) endoplasmic reticulum (Gria1)
plasma membrane (Gria1) cytoplasmic membrane-bounded vesicle (BDNF) protein complex (Gria1)
BDNF (Homo sapiens)
Gria1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate receptor 3 98.56 Very High Very High Very High
tetrodotoxin 1 88.48 High High
Nerve growth factor 1 74.28 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, the mitogen activated protein (MAP) kinase inhibitor PD98059 enhances BDNF-induced glutamate receptor-1 (GluR1) protein expression, but a phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 strongly reduces BDNF-induced GluR1 protein expression.
BDNF Positive_regulation (induced) of Gene_expression (expression) of GluR1 associated with glutamate receptor
1) Confidence 0.03 Published 2002 Journal Neuropharmacology Section Abstract Doc Link 12069900 Disease Relevance 0 Pain Relevance 0.26

General Comments

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