INT103496

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.39
First Reported 2002
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 3.22
Pain Relevance 1.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Vps52) Golgi apparatus (Vps52)
Anatomy Link Frequency
neurons 1
pancreas 1
Vps52 (Rattus norvegicus)
Vps52 - G20210A (1)
Pain Link Frequency Relevance Heat
Nav1.7 10 99.96 Very High Very High Very High
sodium channel 17 99.80 Very High Very High Very High
hyperexcitability 20 99.12 Very High Very High Very High
nav1.8 13 93.88 High High
Neuropathic pain 11 92.64 High High
imagery 1 90.96 High High
Chronic pancreatitis 8 87.60 High High
headache 1 82.16 Quite High
Sciatic nerve 9 81.00 Quite High
dorsal root ganglion 73 80.64 Quite High
Disease Link Frequency Relevance Heat
Adenoma 3 99.32 Very High Very High Very High
Malignant Neoplastic Disease 3 97.96 Very High Very High Very High
Cancer 3 95.40 Very High Very High Very High
Carcinoma 4 95.32 Very High Very High Very High
Neuropathic Pain 14 92.64 High High
Diplopia 1 88.36 High High
Pancreatitis 8 87.60 High High
Paresis 1 86.72 High High
Epilepsy 1 85.68 High High
Vomiting 2 83.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The presence of the p53 mutation protein was observed in carcinomatous pancreatic cells in malignant lesions of the pancreas in primary and transplantable cancers, but was not detected in benign proliferative lesions and adenomas.
Gene_expression (presence) of p53 mutation protein in pancreas associated with adenoma, malignant neoplastic disease and cancer
1) Confidence 0.39 Published 2002 Journal Eur J Gastroenterol Hepatol Section Abstract Doc Link 12072602 Disease Relevance 1.61 Pain Relevance 0.54
Furthermore, factor V Leiden mutation, prothrombin mutation G20210A and MTHFR mutation were searched for.
Gene_expression (searched) of prothrombin mutation G20210A (G20210A)
2) Confidence 0.01 Published 2004 Journal Neurol. Sci. Section Abstract Doc Link 15624088 Disease Relevance 0.89 Pain Relevance 0.13
It is shown that a single sodium channel (Nav1.7) mutation can produce opposing phenotypes (hyperexcitability vs hypoexcitability) in sensory neurons and sympathetic neurons, respectively, and the selective presence of the Nav1.8 channel is a major determinant of these opposing effects.
Gene_expression (produce) of mutation in neurons associated with sodium channel, nav1.8, hyperexcitability and nav1.7
3) Confidence 0.01 Published 2008 Journal Mol Pain Section Body Doc Link PMC2427019 Disease Relevance 0.72 Pain Relevance 1.11

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox