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Context Info
Confidence 0.47
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.24
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Mt2A) intracellular (Mt2A) cytoplasm (Mt2A)
Anatomy Link Frequency
margin 1
Mt2A (Rattus norvegicus)
Pain Link Frequency Relevance Heat
calcitonin gene related peptide 1 88.84 High High
qutenza 3 73.60 Quite High
antagonist 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Ulcers 23 99.56 Very High Very High Very High
Peptic Ulcer 4 85.68 High High
Increased Venous Pressure Under Development 2 76.80 Quite High
Fistula 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that (1) exogenous melatonin and that derived from its precursor, L-tryptophan, accelerate ulcer healing probably via interaction with MT2 receptors; (2) this ulcer healing action is caused by an enhancement by melatonin of the microcirculation at the ulcer margin possibly mediated by COX-derived PG and NO because of overexpression of iNOS and (3) gastrin, which exhibits trophic activity in the gastric mucosa and calcitonin gene related peptide (CGRP), released from sensory nerves, may also contribute to the ulcer healing action of melatonin.
MT2 Binding (interaction) of in margin associated with calcitonin gene related peptide and ulcers
1) Confidence 0.47 Published 2002 Journal J. Pineal Res. Section Abstract Doc Link 12074098 Disease Relevance 1.24 Pain Relevance 0.12

General Comments

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