INT103553

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Context Info
Confidence 0.01
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (MTX1)
MTX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
methotrexate 15 100.00 Very High Very High Very High
antagonist 2 94.64 High High
Dextromethorphan 4 93.44 High High
agonist 1 69.68 Quite High
headache 1 52.92 Quite High
intrathecal 1 44.84 Quite Low
Inflammation 1 42.96 Quite Low
Disease Link Frequency Relevance Heat
Hemiplegia 1 91.24 High High
Dysarthria 1 90.52 High High
Drug Induced Neurotoxicity 3 75.00 Quite High
Convulsion 1 55.16 Quite High
Neurologic Manifestations 1 54.60 Quite High
Headache 1 52.92 Quite High
Affective Disorder 1 51.96 Quite High
Disease 1 43.32 Quite Low
INFLAMMATION 1 42.96 Quite Low
Malignant Neoplastic Disease 1 42.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data provide additional clinical support for elevated CSF Hcy in the induction of MTX-Ntox through activation of the NMDA-receptor.
Positive_regulation (elevated) of Positive_regulation (induction) of MTX-Ntox associated with methotrexate
1) Confidence 0.01 Published 2002 Journal Pediatr Hematol Oncol Section Abstract Doc Link 12078863 Disease Relevance 0.53 Pain Relevance 0.69

General Comments

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