INT103658

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Context Info
Confidence 0.69
First Reported 2002
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.45
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Muc4) extracellular region (Muc4) cell adhesion (Muc4)
endoplasmic reticulum (Muc4) plasma membrane (Muc4) protein complex (Muc4)
Anatomy Link Frequency
covering 2
Muc4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 16 58.84 Quite High
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 32 98.20 Very High Very High Very High
Adenocarcinoma 22 97.32 Very High Very High Very High
Malignant Neoplastic Disease 6 93.64 High High
Adhesions 3 88.56 High High
Pancreatitis 22 88.24 High High
Adenoma 3 87.16 High High
Carcinoma 3 86.84 High High
Pancreatic Cancer 33 84.32 Quite High
Metaplasia 1 54.60 Quite High
Hyperplasia 2 15.16 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MUC4 expression increases progressively in pancreatic intraepithelial neoplasia.
Positive_regulation (increases) of Gene_expression (expression) of MUC4 associated with cancer
1) Confidence 0.69 Published 2002 Journal Am. J. Clin. Pathol. Section Title Doc Link 12090430 Disease Relevance 0.71 Pain Relevance 0.06
In addition to its involvement in the covering of luminal epithelia, recent studies suggest that the overexpression of the MUC4 rat homologue sialomucin complex (SMC) disrupts integrin-mediated cell-matrix and cell-cell interaction and inhibits immune recognition [33].
Positive_regulation (overexpression) of Gene_expression (overexpression) of sialomucin complex in covering
2) Confidence 0.67 Published 2003 Journal Mol Cancer Section Body Doc Link PMC149423 Disease Relevance 0.74 Pain Relevance 0.06

General Comments

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