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Context Info
Confidence 0.04
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.87
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (RETNLB) extracellular region (RETNLB) molecular_function (RETNLB)
cellular_component (RETNLB)
Anatomy Link Frequency
hepatocytes 1
T cell 1
RETNLB (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 56 100.00 Very High Very High Very High
corticosteroid 31 99.98 Very High Very High Very High
cytokine 8 99.96 Very High Very High Very High
Inflammatory response 6 99.80 Very High Very High Very High
cINOD 1 97.52 Very High Very High Very High
Inflammatory mediators 5 77.68 Quite High
dexamethasone 21 67.20 Quite High
withdrawal 2 51.28 Quite High
Inflammatory marker 5 35.92 Quite Low
metalloproteinase 1 19.84 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 70 100.00 Very High Very High Very High
Apoptosis 4 98.20 Very High Very High Very High
Disorder Of Lipid Metabolism 1 97.96 Very High Very High Very High
Asthma 101 96.56 Very High Very High Very High
Amyloidosis 45 93.48 High High
Renal Disease 1 91.24 High High
Alzheimer's Dementia 19 87.48 High High
Cancer 5 86.32 High High
Acute-phase Reaction 4 82.52 Quite High
Disease 14 81.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because of its crucial role in the regulation of pro-inflammatory genes, NF-kappa B is a promising target for the discovery of anti-inflammatory drugs.
Regulation (regulation) of pro-inflammatory associated with inflammation and cinod
1) Confidence 0.04 Published 2002 Journal Drug Discov. Today Section Abstract Doc Link 12110242 Disease Relevance 0.61 Pain Relevance 0.18
SAA is an apolipoprotein constituent of high-density lipoprotein that is synthesized by hepatocytes under the transcriptional regulation of pro-inflammatory cytokins [2].
Regulation (regulation) of pro-inflammatory in hepatocytes associated with inflammation and disorder of lipid metabolism
2) Confidence 0.01 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2911467 Disease Relevance 1.70 Pain Relevance 0.24
In summary, we demonstrate impaired corticosteroid modulation of the pro-inflammatory lipid mediator LTB4 but not of the anti-inflammatory lipoxin, LXA4, in AMs of severe asthma.
Regulation (modulation) of pro-inflammatory associated with asthma, corticosteroid and inflammation
3) Confidence 0.00 Published 2010 Journal Respir Res Section Body Doc Link PMC2894769 Disease Relevance 1.24 Pain Relevance 0.39
The profile of genes suggests a pro-inflammatory response, with up-regulation of IL-1, a pro-inflammatory cytokine that induces T cell activation.
Regulation (regulation) of pro-inflammatory in T cell associated with inflammatory response, inflammation and cytokine
4) Confidence 0.00 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1775064 Disease Relevance 0.32 Pain Relevance 0.21

General Comments

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