INT103889

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Context Info
Confidence 0.03
First Reported 2002
Last Reported 2002
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.15

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mitochondrion (Creb1) nucleus (Creb1) plasma membrane (Pdyn)
DNA binding (Creb1) transcription factor binding (Creb1)
Pdyn (Mus musculus)
Creb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Dynorphin 1 100.00 Very High Very High Very High
Enkephalin 2 99.92 Very High Very High Very High
Disease Link Frequency Relevance Heat
Targeted Disruption 2 99.12 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The combined immunohistochemistry and in situ hybridization protocol was used to examine colocalization of enkephalin or dynorphin mRNA, both downstream targets of CREB-mediated gene expression, in cells expressing transgenic mCREB or CREB.
dynorphin mRNA Spec (examine) Regulation (targets) of Gene_expression (expression) of CREB-mediated associated with targeted disruption, dynorphin and enkephalin
1) Confidence 0.03 Published 2002 Journal Brain Res. Brain Res. Protoc. Section Abstract Doc Link 12113781 Disease Relevance 0.19 Pain Relevance 0.15

General Comments

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