INT103944

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Context Info
Confidence 0.41
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.17
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
fat 1
skin 1
Synm (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropeptide 1 99.96 Very High Very High Very High
fibrosis 53 99.50 Very High Very High Very High
Cholecystokinin 4 96.80 Very High Very High Very High
Bile 22 91.76 High High
Inflammatory stimuli 1 78.04 Quite High
Inflammation 4 75.16 Quite High
cytokine 4 73.28 Quite High
Opioid 2 71.68 Quite High
antagonist 3 10.16 Low Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cirrhosis 78 99.50 Very High Very High Very High
Obesity 3 99.28 Very High Very High Very High
Liver Disease 3 95.08 Very High Very High Very High
Hepatotoxicity 6 82.40 Quite High
INFLAMMATION 5 77.72 Quite High
Body Weight 10 76.84 Quite High
Necrosis 4 74.48 Quite High
Syndrome 1 74.40 Quite High
Apoptosis 2 74.32 Quite High
Fibrosis 33 72.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DMNL rats on high-fat diets do not get as obese as controls, which may be due to a reduction of DMN neuropeptide Y (NPY).
Negative_regulation (reduction) of DMN in fat associated with obesity and neuropeptide
1) Confidence 0.41 Published 2002 Journal Physiol. Behav. Section Abstract Doc Link 12117580 Disease Relevance 0.69 Pain Relevance 0.36
The grape skin and seed treatment blocked these DMN-induced reductions in serum and total protein.
Negative_regulation (blocked) of DMN in skin
2) Confidence 0.14 Published 2010 Journal Nutrition Research and Practice Section Body Doc Link PMC2981719 Disease Relevance 0.89 Pain Relevance 0.28
The development of hepatic fibrosis by dimethylnitrosamine (DMN) in rats was markedly reduced by adenoviral vectors expressing either a truncated human T?
Negative_regulation (reduced) of DMN associated with fibrosis and cirrhosis
3) Confidence 0.08 Published 2003 Journal BMC Gastroenterol Section Body Doc Link PMC270053 Disease Relevance 0.59 Pain Relevance 0.19

General Comments

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