INT103974

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Context Info
Confidence 0.67
First Reported 2001
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.82
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Prss1) extracellular space (Prss1) extracellular region (Prss1)
Prss1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 17 94.48 High High
Pain 3 50.00 Quite Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 1 95.48 Very High Very High Very High
Pancreatitis 19 94.48 High High
Pain 1 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PRSS1 mutations were detected in 52 patients (85.2%): p.R122H (67.2%), p.N29I (14.8%), p.E79K (1.6%), p.N29T (1.6%).
Gene_expression (detected) of PRSS1
1) Confidence 0.67 Published 2009 Journal Ned Tijdschr Geneeskd Section Body Doc Link 19857283 Disease Relevance 0.07 Pain Relevance 0
In 15 patients, we detected a PRSS1 mutation (8 with A16V, 5 with R122H, 2 with N29I), and in 34 patients, a SPINK1 mutation (30 with N34S, 4 with others).
Gene_expression (mutation) of PRSS1
2) Confidence 0.41 Published 2001 Journal Pancreatology Section Abstract Doc Link 12120220 Disease Relevance 0.65 Pain Relevance 0.56
RESULTS: No R122H mutation was found in the PRSS1 gene, and N29I mutation was detected in 7.7% of CP patients.
Neg (No) Gene_expression (found) of PRSS1 gene
3) Confidence 0.34 Published 2009 Journal Pancreatology Section Body Doc Link 19657220 Disease Relevance 0.09 Pain Relevance 0

General Comments

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