INT104005

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Context Info
Confidence 0.42
First Reported 2002
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 4.82
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DES) cytoskeleton (DES) intracellular (DES)
cytoskeleton organization (DES) cytoplasm (DES)
Anatomy Link Frequency
muscle 4
stomach 2
DES (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 10 84.96 Quite High
headache 3 83.84 Quite High
Bile 1 73.68 Quite High
Inflammatory response 1 37.52 Quite Low
Pain 4 25.00 Low Low
cva 3 17.16 Low Low
abdominal pain 2 14.88 Low Low
Disease Link Frequency Relevance Heat
Clear Cell Sarcoma 28 100.00 Very High Very High Very High
Rhinitis 4 98.36 Very High Very High Very High
Cancer 66 97.76 Very High Very High Very High
Injury 1 97.36 Very High Very High Very High
Medulloblastoma 15 97.20 Very High Very High Very High
Ganglion Cysts 3 96.72 Very High Very High Very High
Rhabdoid Tumor 1 93.32 High High
Pressure And Volume Under Development 3 85.72 High High
Headache 3 83.84 Quite High
Myalgia 6 82.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In animal models of eccentric exercise-induced injury, disruption of the cytoskeleton and the sarcolemma of muscle fibres occurs within the first hour after the exercise, since a rapid loss of staining of desmin, a cytoskeletal protein, and the presence of fibronectin, a plasma and extracellular protein, are observed within the muscle fibres.
Negative_regulation (loss) of Gene_expression (staining) of desmin in muscle associated with injury
1) Confidence 0.42 Published 2002 Journal Histochem. Cell Biol. Section Abstract Doc Link 12122444 Disease Relevance 0.64 Pain Relevance 0
Immunohistochemical staining revealed diffuse expression of synaptophysin and neurofilament protein, and focal expression of glial fibrillary acidic protein, S-100 protein, desmin, and myoglobin.
Negative_regulation (revealed) of Gene_expression (expression) of desmin
2) Confidence 0.41 Published 2008 Journal Brain Tumor Pathol Section Abstract Doc Link 18415665 Disease Relevance 0.73 Pain Relevance 0.09
Immunohistochemical staining revealed diffuse expression of neurofilament protein, desmin, and myoglobin.
Negative_regulation (revealed) of Gene_expression (expression) of desmin
3) Confidence 0.41 Published 2008 Journal Brain Tumor Pathol Section Abstract Doc Link 18415665 Disease Relevance 0.69 Pain Relevance 0.11
Immunohistochemical staining revealed diffuse expression of neurofilament protein and focal expression of desmin and myoglobin.
Negative_regulation (revealed) of Gene_expression (expression) of desmin
4) Confidence 0.41 Published 2008 Journal Brain Tumor Pathol Section Abstract Doc Link 18415665 Disease Relevance 0.56 Pain Relevance 0.13
In our case the immunohistochemical studies revealed expression to vimentin, desmin, but not to muscle-specific actin, S-100-protein and cytokeratin.
Neg (not) Negative_regulation (revealed) of Gene_expression (expression) of desmin in muscle
5) Confidence 0.41 Published 2006 Journal World J Surg Oncol Section Body Doc Link PMC1403776 Disease Relevance 0.61 Pain Relevance 0.04
However, to the best of our knowledge, desmin expression by CCS cells has not been described previously [13,19] and CD99 immunoreactivity has been found only in one molecularly confirmed case of CCS of the stomach [20].
Neg (not) Negative_regulation (described) of Gene_expression (expression) of desmin in stomach associated with clear cell sarcoma
6) Confidence 0.41 Published 2010 Journal Mol Cytogenet Section Body Doc Link PMC2908072 Disease Relevance 1.59 Pain Relevance 0

General Comments

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