INT104006

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Context Info
Confidence 0.26
First Reported 2002
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 26
Total Number 26
Disease Relevance 8.09
Pain Relevance 2.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Kdm5d) nucleus (Kdm5d) intracellular (Kdm5d)
DNA binding (Kdm5d)
Anatomy Link Frequency
Heart 1
Kdm5d (Mus musculus)
Pain Link Frequency Relevance Heat
spondylitis 2 99.26 Very High Very High Very High
depression 206 99.20 Very High Very High Very High
backache 3 98.60 Very High Very High Very High
Pain 77 95.52 Very High Very High Very High
Angina 47 92.88 High High
visual analogue scale 71 83.60 Quite High
spinal inflammation 7 75.00 Quite High
addiction 1 10.00 Low Low
alcohol 5 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 561 99.52 Very High Very High Very High
Low Back Pain 12 99.26 Very High Very High Very High
Depression 208 99.20 Very High Very High Very High
Diabetes Mellitus 120 98.92 Very High Very High Very High
Mental Disorders 91 98.32 Very High Very High Very High
Disease 190 98.14 Very High Very High Very High
Injury 145 97.52 Very High Very High Very High
Obesity 14 97.12 Very High Very High Very High
Pain 75 95.52 Very High Very High Very High
Cv General 3 Under Development 47 92.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the univariate analysis, patient global assessment, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) had a good correlation with the EQ-5D values (Pearson's product moment correlation coefficient r > 0.6) whereas physician global assessment, patient pain assessment, and cervical rotation had a moderate correlation with the EQ-5D (0.6 > r > 0.4).
EQ-5D Binding (correlation) of associated with low back pain, pain, spondylitis and disease
1) Confidence 0.26 Published 2009 Journal Clin. Rheumatol. Section Abstract Doc Link 18825472 Disease Relevance 0.90 Pain Relevance 0.48
CONCLUSIONS: Mapping of the EQ-5D index in cardiac patients from demographics and commonly measured cardiac outcome variables is possible; however, prediction for values of the EQ-5D index below 0.4 was not accurate.
EQ-5D Binding (index) of
2) Confidence 0.16 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link 20525323 Disease Relevance 0 Pain Relevance 0
The EQ-5D Index can be linked directly to empirical values for health status of the general public, which allows the conversion to utilities [15].


EQ-5D Binding (linked) of
3) Confidence 0.16 Published 2008 Journal BMC Health Serv Res Section Body Doc Link PMC2543011 Disease Relevance 0.32 Pain Relevance 0.13
Such models could be used to predict the EQ-5D index in cases where it was not administered.
EQ-5D Binding (index) of
4) Confidence 0.14 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC2900231 Disease Relevance 0.20 Pain Relevance 0
The EQ-5D is currently recommended by the UK's National Institute for Health and Clinical Excellence (NICE) as a tool for quantifying utility in adults [3,4].
EQ-5D Binding (recommended) of
5) Confidence 0.14 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC2900231 Disease Relevance 0 Pain Relevance 0
The RMSEs were also higher for EQ-5D <= 0.4 in both datasets.
EQ-5D Binding (higher) of
6) Confidence 0.14 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC2900231 Disease Relevance 0.09 Pain Relevance 0.09
Response rates for the instruments were >90% and statistical modelling revealed an association between EQ-5D and Minnesota Living with Heart Failure scores.
EQ-5D Binding (association) of in Heart
7) Confidence 0.11 Published 2005 Journal Eur. J. Heart Fail. Section Body Doc Link 15701474 Disease Relevance 0.18 Pain Relevance 0
The signs associated with the EQ-5D domain coefficients, and the relative magnitudes associated with the severity of problem reported, are as would be expected.
EQ-5D Binding (associated) of
8) Confidence 0.10 Published 2008 Journal Health Qual Life Outcomes Section Body Doc Link PMC2588564 Disease Relevance 0.17 Pain Relevance 0.17
However, when adjusted for background data, most ICU variables are no longer associated with EQ-5D.
EQ-5D Neg (no) Binding (associated) of
9) Confidence 0.09 Published 2002 Journal Intensive Care Med Section Body Doc Link 12122528 Disease Relevance 0 Pain Relevance 0
The 'physical health' domain score of the WHOQOL-BREF showed strong association with all EQ-5D dimensions as well as strong correlation with EQ VAS and EQ-5D index scores.
EQ-5D Binding (association) of
10) Confidence 0.09 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC2873595 Disease Relevance 0.62 Pain Relevance 0.08
For almost all EQ-5D dimensions, different response levels were associated with significantly different scores of the WHOQOL-BREF domains and measures of psychopathology.
EQ-5D Binding (associated) of
11) Confidence 0.09 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC2873595 Disease Relevance 0.75 Pain Relevance 0.17
The 'physical health' domain score of the WHOQOL-BREF showed strong association with all EQ-5D dimensions as well as strong correlation with EQ VAS and EQ-5D index scores.
EQ-5D Binding (association) of
12) Confidence 0.09 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC2873595 Disease Relevance 0.64 Pain Relevance 0.08
Also, as hypothesized, a very strong association of the EQ-5D dimension 'anxiety/depression' with the 'mental health' domain score of the WHOQOL-BREF (d = 1.44) was found, but also with the BDI-II (d = 1.52).
EQ-5D Binding (association) of associated with mental disorders, depression and anxiety disorder
13) Confidence 0.08 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC2873595 Disease Relevance 0.82 Pain Relevance 0.17
Validity was analyzed by assessing associations between EQ-5D scores and related other scores.
EQ-5D Binding (associations) of
14) Confidence 0.08 Published 2010 Journal Health Qual Life Outcomes Section Abstract Doc Link PMC2873595 Disease Relevance 0.54 Pain Relevance 0.03
The EuroSafe Group has developed guidelines which advise the use of a combination of the EQ-5D and the HUI, with assessments at 1, 2, 4 and 12 months after injury [1].
EQ-5D Binding (combination) of associated with injury
15) Confidence 0.07 Published 2010 Journal BMC Public Health Section Body Doc Link PMC3019196 Disease Relevance 0.38 Pain Relevance 0
EQ-5D seems to correlate with both the severity of symptoms and the cumulative exposure index, and can thus be recommended as part of the health examination of workers exposed to HAV.


EQ-5D Binding (recommended) of
16) Confidence 0.06 Published 2010 Journal Int Arch Occup Environ Health Section Body Doc Link 19593581 Disease Relevance 0 Pain Relevance 0
In the case of the EQ-5D, this implies the integration of dimensions such as anxiety/depression and physical mobility, which may not initially appear to be closely related, but may be combined for the purpose of a common, second degree dimensionality that could be called 'General Health'.
EQ-5D Binding (integration) of associated with depression and anxiety disorder
17) Confidence 0.05 Published 2004 Journal BMC Med Res Methodol Section Body Doc Link PMC415546 Disease Relevance 0.20 Pain Relevance 0.05
As the analysis involves a comparison of the EQ-5D with the SF-36 we have restricted the analysis to the Australian patients.


EQ-5D Binding (comparison) of
18) Confidence 0.05 Published 2007 Journal Health Qual Life Outcomes Section Body Doc Link PMC1950473 Disease Relevance 0.41 Pain Relevance 0.16
The levels 'moderate problems' and 'extreme problems' were combined into one category, since the number of respondents reporting 'extreme problems' was small for most EQ-5D dimensions.
EQ-5D Binding (dimensions) of
19) Confidence 0.05 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC3009699 Disease Relevance 0 Pain Relevance 0
For comparison with studies from other countries, an EQ-5D index based on the UK tariff according to Dolan [16] was calculated additionally.
EQ-5D Binding (index) of
20) Confidence 0.03 Published 2010 Journal Health Qual Life Outcomes Section Body Doc Link PMC2864208 Disease Relevance 0.40 Pain Relevance 0.03

General Comments

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