INT104012

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Context Info
Confidence 0.14
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pdpk1) cytoplasmic membrane-bounded vesicle (Pdpk1) plasma membrane (Pdpk1)
nucleus (Pdpk1) kinase activity (Pdpk1) cytoplasm (Pdpk1)
Anatomy Link Frequency
spinal 2
Pdpk1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
intrathecal 5 99.16 Very High Very High Very High
Morphine 12 98.92 Very High Very High Very High
tolerance 8 98.56 Very High Very High Very High
Kinase C 4 92.68 High High
withdrawal 1 89.68 High High
analgesia 1 75.52 Quite High
Analgesic 1 58.40 Quite High
Spinal cord 2 25.00 Low Low
opiate 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we examined the effect of intrathecal delivery of an antisense oligonucleotide targeting rat protein kinase Calpha mRNA on the expression of spinal protein kinase Calpha isozyme and spinal morphine tolerance.
Regulation (targeting) of Transcription (expression) of protein kinase in spinal associated with tolerance, morphine and intrathecal
1) Confidence 0.14 Published 2002 Journal Neuroscience Section Abstract Doc Link 12123688 Disease Relevance 0 Pain Relevance 1.20

General Comments

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