INT104069

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Context Info
Confidence 0.60
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.68
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (RHO) plasma membrane (RHO) signal transducer activity (RHO)
Anatomy Link Frequency
coronary artery 1
RHO (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 7 99.84 Very High Very High Very High
cINOD 2 94.52 High High
Glutamate receptor 1 91.68 High High
Angina 1 88.80 High High
anesthesia 1 74.40 Quite High
cytokine 2 58.16 Quite High
Inflammation 1 25.00 Low Low
chemokine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 7 99.84 Very High Very High Very High
Cancer 10 99.80 Very High Very High Very High
Osteogenic Sarcomas 1 95.68 Very High Very High Very High
Metastasis 1 94.76 High High
INFLAMMATION 3 94.32 High High
Acute Coronary Syndrome 1 90.20 High High
Angina 1 88.80 High High
Adhesions 2 86.76 High High
Stress 4 85.44 High High
Spasticity 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that propofol inhibits the invasion ability of cancer cells by modulating Rho A and this agent might be an ideal anesthetic for cancer surgery.
Regulation (modulating) of Rho associated with cancer
1) Confidence 0.60 Published 2002 Journal Cancer Lett. Section Abstract Doc Link 12127688 Disease Relevance 0.79 Pain Relevance 0.07
We examined the genetic variability of Rho-family GTPases and their regulators in coronary artery spasm.
Regulation (regulators) of Rho in coronary artery associated with cva
2) Confidence 0.44 Published 2010 Journal J. Hum. Genet. Section Abstract Doc Link 19911011 Disease Relevance 0.73 Pain Relevance 0.33
includes the rhodopsin-like GPCRs, the secretin-like GPCRs, the cAMP receptors,
Regulation (includes) of rhodopsin
3) Confidence 0.44 Published 2008 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2276817 Disease Relevance 0 Pain Relevance 0.07
Immunomodulatory drugs reorganize cytoskeleton by modulating Rho GTPases.
Regulation (modulating) of Rho
4) Confidence 0.26 Published 2009 Journal Blood Section Title Doc Link 19417207 Disease Relevance 0.16 Pain Relevance 0.09

General Comments

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