INT104110

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Context Info
Confidence 0.00
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adrbk2, Oprm1) cytosol (Adrbk2) plasma membrane (Oprm1)
nucleus (Adrbk2) cilium (Adrbk2) signal transducer activity (Oprm1)
Adrbk2 (Rattus norvegicus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
mu opioid receptor 3 88.64 High High
agonist 1 84.00 Quite High
Kinase C inhibitor 1 79.60 Quite High
orphanin 4 75.00 Quite High
opioid receptor 2 75.00 Quite High
Kinase C 1 75.00 Quite High
Opioid 1 68.64 Quite High
tolerance 2 66.96 Quite High
Morphine 2 66.56 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reduction of GRK2 and GRK3 levels by antisense, but not sense DNA treatment blocks ORL1 and mu receptor desensitization.
Negative_regulation (Reduction) of GRK3 Negative_regulation (blocks) of mu receptor
1) Confidence 0.00 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12130708 Disease Relevance 0 Pain Relevance 0.71

General Comments

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