INT104143

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.67
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 8
Disease Relevance 8.10
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

RNA binding (EWSR1) plasma membrane (EWSR1) nucleus (EWSR1)
intracellular (EWSR1) cytoplasm (EWSR1)
EWSR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 89.60 High High
Dysuria 1 86.48 High High
abdominal pain 3 80.00 Quite High
imagery 6 72.64 Quite High
Pain 4 70.68 Quite High
lumbar region 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sarcoma 30 99.76 Very High Very High Very High
Cancer 159 99.68 Very High Very High Very High
Clear Cell Sarcoma 56 99.28 Very High Very High Very High
Desmoplastic Small Round Cell Tumor 15 96.78 Very High Very High Very High
Residual Neoplasm 2 95.12 Very High Very High Very High
Disease 6 92.84 High High
Bone Cancer 19 90.96 High High
INFLAMMATION 2 89.60 High High
Leukemia 3 89.32 High High
Metastasis 10 88.52 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Desmoplastic small round cell tumor is a rare, aggressive neoplasm that mainly affects young male patients and is characterized by a reciprocal translocation t(11;22)(p13;q12) associated with the EWS-WT1 gene fusion transcript.
Transcription (transcript) of EWS associated with desmoplastic small round cell tumor and cancer
1) Confidence 0.67 Published 2002 Journal Am. J. Surg. Pathol. Section Abstract Doc Link 12131150 Disease Relevance 0.91 Pain Relevance 0.08
This study emphasizes the utility of analysis of the EWS-WT1 gene fusion transcript, which was performed on paraffin-embedded tissues, to confirm the diagnosis.
Transcription (transcript) of EWS
2) Confidence 0.67 Published 2002 Journal Am. J. Surg. Pathol. Section Abstract Doc Link 12131150 Disease Relevance 0.92 Pain Relevance 0
The EWS-WT1 gene fusion transcript was detected in 29 of 30 tumors.
Transcription (detected) of EWS associated with cancer
3) Confidence 0.52 Published 2002 Journal Am. J. Surg. Pathol. Section Abstract Doc Link 12131150 Disease Relevance 1.29 Pain Relevance 0.07
Immunoreactivity for CD99 and detection of the EWS-FLI1 hybrid transcripts are important for the correct diagnosis of ESFT arising in an unusual location.
Transcription (transcripts) of EWS associated with cancer
4) Confidence 0.52 Published 2006 Journal Tohoku J. Exp. Med. Section Abstract Doc Link 16864960 Disease Relevance 0.93 Pain Relevance 0.11
Wang et al [14] found the EWSR1-CREB1 chimeric transcript in 1 of 15 cases (~7%), a superficial tumor in the palm of a 66-year-old female.
Transcription (transcript) of EWSR1 associated with cancer
5) Confidence 0.52 Published 2010 Journal Mol Cytogenet Section Body Doc Link PMC2908072 Disease Relevance 1.19 Pain Relevance 0
Interestingly, the rate of detection of EWSR1 rearrangement in CCS by FISH has been variously reported to be 70%, 88% or 100% [18,22,23], raising the possibility of EWSR1 being substituted by other genes as a 5'partner in a small subset of CCS.
Transcription (detection) of EWSR1 associated with clear cell sarcoma
6) Confidence 0.52 Published 2010 Journal Mol Cytogenet Section Body Doc Link PMC2908072 Disease Relevance 0.87 Pain Relevance 0
For example, the two most frequent exon combinations in EwingÂ’s sarcoma-associated EWS/FLI1 fusion transcripts include fusion of EWS exon 7 to FLI1 exon 6 (type I) and fusion of EWS exon 7 to FLI1 exon 5 (type II).
Transcription (transcripts) of EWS associated with sarcoma
7) Confidence 0.36 Published 2008 Journal J Orthop Sci Section Body Doc Link PMC2778709 Disease Relevance 0.79 Pain Relevance 0.08
EWS-FLI1 fusion transcripts were detected in the tumor tissue by reverse transcriptase polymerase chain reaction.
Transcription (detected) of EWS-FLI1 associated with cancer
8) Confidence 0.09 Published 2007 Journal J. Pediatr. Hematol. Oncol. Section Abstract Doc Link 18090934 Disease Relevance 1.21 Pain Relevance 0.09

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox