INT104168

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Context Info
Confidence 0.89
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.31
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Nfasc) plasma membrane (Nfasc)
Nfasc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
transdermal 25 99.84 Very High Very High Very High
tetrodotoxin 3 87.84 High High
Action potential 3 80.32 Quite High
Inflammation 2 63.52 Quite High
alcohol 11 33.12 Quite Low
anesthesia 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 15 95.28 Very High Very High Very High
Pressure And Volume Under Development 1 64.24 Quite High
INFLAMMATION 2 63.52 Quite High
Flushing 4 57.28 Quite High
Burns 17 50.00 Quite Low
Bacterial Respiratory Disease 5 26.96 Quite Low
Sprains And Strains 4 23.84 Low Low
Wound Healing 18 9.44 Low Low
Injury 18 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The degradation of NF in transdermal plasters followed first order, as the values of R2 for time versus log percent degradation graph were high.
Protein_catabolism (degradation) of NF associated with transdermal
1) Confidence 0.89 Published 2010 Journal Eplasty Section Body Doc Link PMC2890388 Disease Relevance 0.19 Pain Relevance 0.18
TTX only partially reduced NF160 degradation.
Protein_catabolism (degradation) of NF160
2) Confidence 0.41 Published 2002 Journal Neurosci. Lett. Section Abstract Doc Link 12133577 Disease Relevance 0.42 Pain Relevance 0.13
Significant calpain-mediated breakdown of NF160 and NF200 indicates structural damage to the axonal cytoskeleton, which was completely Ca(2+)-dependent.
Protein_catabolism (breakdown) of NF200
3) Confidence 0.27 Published 2002 Journal Neurosci. Lett. Section Abstract Doc Link 12133577 Disease Relevance 0.35 Pain Relevance 0.11
Significant calpain-mediated breakdown of NF160 and NF200 indicates structural damage to the axonal cytoskeleton, which was completely Ca(2+)-dependent.
Protein_catabolism (breakdown) of NF160
4) Confidence 0.27 Published 2002 Journal Neurosci. Lett. Section Abstract Doc Link 12133577 Disease Relevance 0.35 Pain Relevance 0.11

General Comments

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