INT104336

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Context Info
Confidence 0.38
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chrm3) plasma membrane (Chrm3) signal transducer activity (Chrm3)
Anatomy Link Frequency
nerve 2
Chrm3 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 7 98.14 Very High Very High Very High
tetrodotoxin 1 97.58 Very High Very High Very High
gABA 2 94.16 High High
agonist 1 73.88 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additional release studies performed in the presence of tetrodotoxin suggested that the dopamine release-stimulating M4 receptors are probably located on neuronal cell bodies, but that the release-facilitating M5 and the release-inhibiting M3 receptors are likely to be located on nerve terminals.
Positive_regulation (release-facilitating) of Localization (release) of M3 in nerve associated with tetrodotoxin and dopamine
1) Confidence 0.38 Published 2002 Journal J. Neurosci. Section Abstract Doc Link 12151512 Disease Relevance 0.14 Pain Relevance 0.50

General Comments

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