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Context Info
Confidence 0.37
First Reported 2002
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.83
Pain Relevance 1.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk9) mitochondrion (Mapk9) nucleus (Mapk9)
transcription factor binding (Mapk9) cytoplasm (Mapk9)
Mapk9 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cva 13 98.08 Very High Very High Very High
Inflammation 53 96.48 Very High Very High Very High
Inflammatory response 4 94.32 High High
anesthesia 1 90.00 High High
Arthritis 32 86.16 High High
tolerance 3 84.72 Quite High
adenocard 3 82.88 Quite High
cytokine 12 81.12 Quite High
Pain 8 77.76 Quite High
intrathecal 37 76.92 Quite High
Disease Link Frequency Relevance Heat
Hemorrhage 13 98.08 Very High Very High Very High
INFLAMMATION 55 96.48 Very High Very High Very High
Stress 3 92.48 High High
Experimental Arthritis 22 86.88 High High
Increased Venous Pressure Under Development 2 78.80 Quite High
Pain 7 77.76 Quite High
Necrosis 3 75.00 Quite High
Glioma 3 75.00 Quite High
Cancer 3 75.00 Quite High
Sepsis 1 73.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The TNF-alpha-induced IL-6 release was suppressed by SB203580, a p38 MAPK inhibitor, or SP600125, a SAPK/JNK inhibitor, but not by PD98059, a MAP kinase/extracellular signal-regulated kinase kinase inhibitor.
Neg (not) Negative_regulation (inhibitor) of SAPK
1) Confidence 0.37 Published 2009 Journal Neurochem. Int. Section Abstract Doc Link 19427347 Disease Relevance 0.82 Pain Relevance 0.23
Intraventricular treatment with CNI-1493, which inhibits p38, c-Jun N-terminal kinase, and perhaps other kinases, suppresses TNF?
Negative_regulation (inhibits) of c-Jun N-terminal kinase
2) Confidence 0.26 Published 2006 Journal PLoS Medicine Section Body Doc Link PMC1560929 Disease Relevance 0.99 Pain Relevance 0.74
Protein was isolated from tissues for determination of p44/42 and SAPK/JNK phosphorylation by Western blot analysis.
Negative_regulation (determination) of SAPK
3) Confidence 0.18 Published 2002 Journal Shock Section Abstract Doc Link 12166775 Disease Relevance 1.02 Pain Relevance 0.71

General Comments

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