INT104482

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Context Info
Confidence 0.49
First Reported 2002
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.55
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk9) mitochondrion (Mapk9) nucleus (Mapk9)
transcription factor binding (Mapk9) cytoplasm (Mapk9)
Mapk9 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cva 13 99.98 Very High Very High Very High
tolerance 4 99.84 Very High Very High Very High
diabetic neuropathy 47 87.20 High High
unmyelinated 2 84.08 Quite High
anesthesia 1 67.24 Quite High
Nerve growth factor 8 58.08 Quite High
cytokine 1 53.28 Quite High
Central nervous system 5 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 9 100.00 Very High Very High Very High
Hemorrhage 13 99.98 Very High Very High Very High
Diabetes Mellitus 67 99.60 Very High Very High Very High
Diabetic Neuropathy 48 87.20 High High
Frailty 5 68.64 Quite High
Sepsis 1 50.56 Quite High
Encephalopathy 6 50.00 Quite Low
Congenital Anomalies 15 27.00 Quite Low
Nervous System Injury 1 25.12 Quite Low
Cognitive Disorder 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The induction of tolerance by SLH leads to phosphorylation of both p44/42 and SAPK/JNK MAP-kinases.
Positive_regulation (leads) of Phosphorylation (phosphorylation) of SAPK associated with tolerance and cva
1) Confidence 0.49 Published 2002 Journal Shock Section Abstract Doc Link 12166775 Disease Relevance 0.85 Pain Relevance 0.65
upregulation of phosphorylating stress kinases like SAPK and GSK-3?
Positive_regulation (upregulation) of Phosphorylation (phosphorylating) of SAPK associated with stress
2) Confidence 0.33 Published 2008 Journal Experimental Diabetes Research Section Body Doc Link PMC2323445 Disease Relevance 0.70 Pain Relevance 0.19

General Comments

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